Daniel Little — Iowa State University

Area of research

Molecular Biology · Neurology

Research interest

Research focused on Cell biology and Mitochondrion, with related work in Mitochondrial permeability transition pore, Lipid peroxidation, Induced pluripotent stem cell. Notable publications include 'α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson’s disease', 'α-Synuclein binds to the ER–mitochondria tethering protein VAPB to disrupt Ca2+ homeostasis and mitochondrial ATP production', and 'Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation'.

Recent publications

Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation

Cell Death and Differentiation 2020cited by 298position: middledoi

α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson’s disease

Nature Communications 2018cited by 501position: middledoi

A single cell high content assay detects mitochondrial dysfunction in iPSC-derived neurons with mutations in SNCA

Scientific Reports 2018cited by 65position: firstdoi

α-Synuclein binds to the ER–mitochondria tethering protein VAPB to disrupt Ca2+ homeostasis and mitochondrial ATP production

Acta Neuropathologica 2017cited by 357position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Paul Gissen · University of Birmingham4 papers (2017–2020)Michael J. Devine · University of Edinburgh4 papers (2017–2020)Sonia Gandhi · Lancashire Teaching Hospitals NHS Foundation Trust3 papers (2018–2020)— · 3 papers (2018–2020)— · 2 papers (2018–2020)Margarida Rodrigues · UK Dementia Research Institute2 papers (2018–2020)— · 2 papers (2018–2020)Zhi Yao · The First Affiliated Hospital, Sun Yat-sen University2 papers (2018–2018)Evgeny V. Pavlov · New York University2 papers (2018–2020)Mathew H. Horrocks · University of Edinburgh2 papers (2018–2020)David Klenerman · UK Dementia Research Institute2 papers (2018–2020)Sébastien Paillusson · Inserm2 papers (2017–2018)Tilo Kunath · University of Edinburgh2 papers (2018–2020)Karamjit Singh Dolt · University of Edinburgh2 papers (2018–2020)— · 2 papers (2018–2020)Ratsuda Yapom · University of Edinburgh2 papers (2018–2020)— · 1 papers (2018–2018)Radu Stoica · Institutul Clinic Fundeni1 papers (2017–2017)Christopher C.J. Miller · King's College London1 papers (2017–2017)Craig D. Hughes · AstraZeneca (Singapore)1 papers (2020–2020)

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