Area of research
Critical Care and Intensive Care Medicine · Physiology
Research interest
Research interests include Trauma, Hemostasis, Coagulopathy, Resuscitation, Erythrocyte Function and Pathophysiology, Metabolomics and Mass Spectrometry Studies, and Cancer, Hypoxia, and Metabolism.
GPX4 regulates lipid peroxidation and ferroptosis of stored red blood cells
Drug screening in 3D microtumors reveals DDR1/2-MAPK12-GLI1 as a vulnerability in cancer-associated fibroblasts
Genetic regulation of carnitine metabolism controls lipid damage repair and aging RBC hemolysis in vivo and in vitro
Ferroptosis regulates hemolysis in stored murine and human red blood cells
Arginine metabolism is a biomarker of red blood cell and human aging
Regulation of kynurenine metabolism by blood donor genetics and biology impacts red cell hemolysis in vitro and in vivo
Proregenerative extracellular matrix hydrogel mitigates pathological alterations of pelvic skeletal muscles after birth injury
Genetic polymorphisms and expression of Rhesus blood group RHCE are associated with 2,3-bisphosphoglycerate in humans at high altitude
Multi-omics analysis of sarcospan overexpression in mdx skeletal muscle reveals compensatory remodeling of cytoskeleton-matrix interactions that promote mechanotransduction pathways
The influenza-injured lung microenvironment promotes MRSA virulence, contributing to severe secondary bacterial pneumonia
Myocardial matrix hydrogel acts as a reactive oxygen species scavenger and supports a proliferative microenvironment for cardiomyocytes
Hemorrhagic shock and tissue injury provoke distinct components of trauma-induced coagulopathy in a swine model
Astrocytic laminin-211 drives disseminated breast tumor cell dormancy in brain
COVID-19 infection alters kynurenine and fatty acid metabolism, correlating with IL-6 levels and renal status
Tumour-associated macrophages drive stromal cell-dependent collagen crosslinking and stiffening to promote breast cancer aggression
Stiff stroma increases breast cancer risk by inducing the oncogene ZNF217
Blood donor exposome and impact of common drugs on red blood cell metabolism
Targeting the perivascular niche sensitizes disseminated tumour cells to chemotherapy
A unified mechanism for intron and exon definition and back-splicing
Red Blood Cell Metabolic Responses to Torpor and Arousal in the Hibernator Arctic Ground Squirrel
Manufacturing considerations for producing and assessing decellularized extracellular matrix hydrogels
Extracellular matrix in lung development, homeostasis and disease
A tension-mediated glycocalyx–integrin feedback loop promotes mesenchymal-like glioblastoma
Evaluation of Different Decellularization Protocols on the Generation of Pancreas-Derived Hydrogels
Biliverdin Reductase B Dynamics Are Coupled to Coenzyme Binding
Structure of the yeast spliceosomal postcatalytic P complex
CryoEM structure of Saccharomyces cerevisiae U1 snRNP offers insight into alternative splicing
Clipping of arginine-methylated histone tails by JMJD5 and JMJD7
Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression
Extracellular Matrix Hydrogel Promotes Tissue Remodeling, Arteriogenesis, and Perfusion in a Rat Hindlimb Ischemia Model