Area of research
Molecular Biology · Neurology
Research interest
Research interests include Histone Deacetylase Inhibitors Research, Neuroblastoma Research and Treatments, Protein Degradation and Inhibitors, and Ubiquitin and proteasome pathways.
The protein deacetylase HDAC10 controls DNA replication in malignant lymphoid cells
Identification of a Proteolysis‐Targeting‐Chimera that Addresses Activated Checkpoint Kinase‐1 Reveals its Non‐Catalytic Functions in Tumor Cells
Selective degradation of mutant FMS-like tyrosine kinase-3 requires BIM-dependent depletion of heat shock proteins
Synergy of retinoic acid and BH3 mimetics in MYC(N)-driven embryonal nervous system tumours
Neuroblastoma response to RAS-MAPK inhibitors and APR-246 (eprenetapopt) co-treatment is dependent on SLC7A11
Transdiagnostic risk of mental disorders in offspring of affected parents: a meta‐analysis of family high‐risk and registry studies
The first-in-class ERK inhibitor ulixertinib shows promising activity in mitogen-activated protein kinase (MAPK)-driven pediatric low-grade glioma models
Functional Therapeutic Target Validation Using Pediatric Zebrafish Xenograft Models
<scp>ERBB</scp> and P‐glycoprotein inhibitors break resistance in relapsed neuroblastoma models through P‐glycoprotein
Evaluation of Antitumor and On-Target Activity of HDAC Inhibitors with the Zebrafish Embryo Xenograft Model
Broad-Spectrum HDAC Inhibitors Promote Autophagy through FOXO Transcription Factors in Neuroblastoma
Combining APR-246 and HDAC-Inhibitors: A Novel Targeted Treatment Option for Neuroblastoma
Rapid In Vivo Validation of HDAC Inhibitor-Based Treatments in Neuroblastoma Zebrafish Xenografts
A kinome-wide RNAi screen identifies ALK as a target to sensitize neuroblastoma cells for HDAC8-inhibitor treatment
Targeted neuroblastoma therapy and the development of autophagy-mediated drug resistance in the zebrafish xenograft model