Area of research
Immunology · Molecular Biology
Research interest
Research interests include Epigenetics and DNA Methylation, Immune Response and Inflammation, NF-κB Signaling Pathways, and Immune cells in cancer.
FCRL3 is an immunoregulatory receptor that restrains the activation of human memory T lymphocytes.
Control of myeloid lineage fidelity and response to stimuli by ISWI-enforced nucleosome phasing.
Leveraging the tug-of-war with genomic retroelements to enhance immunotherapy of pancreatic cancer.
A framework to mine laser microdissection-based omics data and uncover regulators of pancreatic cancer heterogeneity.
Cancer Evolution: A Multifaceted Affair.
Mapping functional to morphological variation reveals the basis of regional extracellular matrix subversion and nerve invasion in pancreatic cancer.
The landscape of cancer-rewired GPCR signaling axes
The landscape of cancer-rewired GPCR signaling axes.
Activation of endogenous retroviruses and induction of viral mimicry by MEK1/2 inhibition in pancreatic cancer.
Acetyl-CoA production by Mediator-bound 2-ketoacid dehydrogenases boosts de novo histone acetylation and is regulated by nitric oxide.
An integrative epigenome-based strategy for unbiased functional profiling of clinical kinase inhibitors.
High-sensitivity analysis of clonal hematopoiesis reveals increased clonal complexity of potential-driver mutations in severe COVID-19 patients.
Learning and actioning general principles of cancer cell drug sensitivity
Cancer Evolution: A Multifaceted Affair
Restrictor synergizes with Symplekin and PNUTS to terminate extragenic transcription.
Interferon regulatory factor 1 (IRF1) controls the metabolic programmes of low-grade pancreatic cancer cells.
ADP-ribosyltransferases, an update on function and nomenclature.
Current challenges in understanding the role of enhancers in disease.
Longitudinal multi-omics analysis identifies early blood-based predictors of anti-TNF therapy response in inflammatory bowel disease.
DNA methyltransferase 3A controls intestinal epithelial barrier function and regeneration in the colon.
H3K9 trimethylation in active chromatin restricts the usage of functional CTCF sites in SINE B2 repeats.
Lower probability and shorter duration of infections after COVID-19 vaccine correlate with anti-SARS-CoV-2 circulating IgGs.
RFX transcription factors control a miR-150/PDAP1 axis that restrains the proliferation of human T cells.
Coexisting morpho-biotypes unveil the regulatory bases of phenotypic plasticity in pancreatic ductal adenocarcinoma
Clonal hematopoiesis, inflammation, and cardiovascular disorders: a mitochondrial connection.
ADP‐ribosyltransferases, an update on function and nomenclature
Epithelial memory of inflammation limits tissue damage while promoting pancreatic tumorigenesis.
A first exon termination checkpoint preferentially suppresses extragenic transcription.
Integration of transcriptional and metabolic control in macrophage activation.
Tumor cell heterogeneity and its transcriptional bases in pancreatic cancer: a tale of two cell types and their many variants.