Area of research
Molecular Biology · Genetics
Research interest
Research interests include Bacterial Genetics and Biotechnology, RNA and protein synthesis mechanisms, Protein Kinase Regulation and GTPase Signaling, and Cellular transport and secretion.
Design, Synthesis, and SAR of Covalent KIT and PDGFRA Inhibitors─Exploring Their Potential in Targeting GIST
Lethal Borna disease virus 1 infections of humans and animals – in-depth molecular epidemiology and phylogeography
Avapritinib-based SAR studies unveil a binding pocket in KIT and PDGFRA
Lethal Borna disease virus 1 (BoDV-1) infections of humans and animals – in-depth molecular epidemiology and phylogeography
Kohlenhydrate, Lipide, Aminosäuren und Nucleotide – Bausteine des Lebens
Cellular model system to dissect the isoform-selectivity of Akt inhibitors
Targeting Her2-insYVMA with Covalent Inhibitors—A Focused Compound Screening and Structure-Based Design Approach
Preclinical Efficacy of Covalent-Allosteric AKT Inhibitor Borussertib in Combination with Trametinib in <i>KRAS</i>-Mutant Pancreatic and Colorectal Cancer
Mobility-Based Quantification of Multivalent Virus-Receptor Interactions: New Insights Into Influenza A Virus Binding Mode
Covalent‐Allosteric Inhibitors to Achieve Akt Isoform‐Selectivity
Inhibition of osimertinib-resistant epidermal growth factor receptor EGFR-T790M/C797S
Covalent‐Allosteric Inhibitors to Achieve Akt Isoform‐Selectivity
Simultaneous impairment of mitochondrial fission and fusion reduces mitophagy and shortens replicative lifespan
Mechanismen der Glucosehomöostase
Kohlenhydrate, Lipide, Aminosäuren und Nucleotide – Bausteine des Lebens