Area of research
Genetics · Clinical Psychology
Research interest
Research focused on Rett syndrome and MECP2, with related work in Inflammasome, Oxidative stress, Inflammation. Notable publications include 'Compromised immune/inflammatory responses in Rett syndrome', 'Alterations of mitochondrial bioenergetics, dynamics, and morphology support the theory of oxidative damage involvement in autism spectrum disorder', and 'Altered inflammasome machinery as a key player in the perpetuation of Rett syndrome oxinflammation'.
Impaired <scp>NF</scp> ‐ <scp>κB</scp> /Nrf2 Crosstalk in Rett Syndrome
Lipid peroxidation-induced cell death in Rett syndrome
Mitochondrial redox imbalance and CoQ10 deficiency in Rett syndrome: Insights from patient-derived fibroblasts
Mitochondrial Redox Imbalance and Coq10 Deficiency in Rett Syndrome: Insights from Patient-Derived Fibroblasts
Abnormal MAMs proteins can disrupt finely tuned signaling between ER and mitochondria in RTT brain
Role of mitochondrial alterations as upstream triggers of NLRP3 inflammasome response in RETT syndrome
Mitochondrial abnormalities and oxinflammatory mechanisms in Rett syndrome presymptomatic/ symptomatic switch
Evidence of compromised redox homeostasis and ferritinophagy in Rett syndrome
NLRP3 inflammasome-mitochondrion loop in autism spectrum disorder
Biochemical and molecular determinants of the subclinical inflammatory mechanisms in Rett syndrome
Evidence of altered redox homeostasis in trichothiodystrophy
Aberrant NLRP3 inflammasome response in Rett syndrome: from ex vivo to in vivo models for investigating pathogenetic mechanisms and new potential therapeutic strategies
Abnormal Mitochondrion-NLRP3 Inflammasome crosstalk in the pathophysiology of Autism Spectrum Disorder
Ox-inflammasome involvement in neuroinflammation
Deregulated NLRP3 inflammasome response due to a constitutive activation of NF-κB p65 pro-inflammatory pathway in lymphomonocytes of Rett syndrome patients
Mitochondrial dysfunction and NLRP3 inflammasome activation in Autism Spectrum Disorder
Constitutive activation of NLRP3 inflammasome machinery in ex-vivo models of Rett syndrome: from pathogenetic role to new potential therapeutic target
Inflammasomes regulation by environmental pollutants in human skin
Omega-3 nutritional intervention as therapeutic co-adjuvant approach to improve Rett syndrome clinical and biochemical features
The pathogenic axis between mitochondrial dysfunction and NLRP3 inflammasome activation in Autism Spectrum Disorder
The constitutive activation of TLR4-IRAK1- NFκB axis is involved in the early NLRP3 inflammasome response in peripheral blood mononuclear cells of Rett syndrome patients
Ubiquitination as a key regulatory mechanism for O3-induced cutaneous redox inflammasome activation
Sirtuins as potential therapeutic targets for mitigating OxInflammation in typical Rett syndrome: plausible mechanisms and evidence
Aberrant Mitochondrial Bioenergetics Fuels Inflammasome Machinery in Autism Spectrum Disorder
[YIA] Evidence of ferroptosis involvement in Rett syndrome pathogenesis
A possible role for the loss of brain Scavenger Receptor B1 (SR-B1) in Rett syndrome
Ubiquitination as a key regulatory mechanism for O3-induced cutaneous redox Inflammasome activation
Impaired mitochondrial quality control in Rett Syndrome
Endothelial cells from umbilical cord of women affected by gestational diabetes: A suitable in vitro model to study mechanisms of early vascular senescence in diabetes
Altered Bone Status in Rett Syndrome