Area of research
Surgery · Cancer Research
Research interest
Research interests include Esophageal Cancer Research and Treatment, Cancer Genomics and Diagnostics, Gastric Cancer Management and Outcomes, and Genetic factors in colorectal cancer.
Evolutionary and immune microenvironment dynamics during neoadjuvant treatment of esophageal adenocarcinoma
PARP1-targeted fluorescence molecular endoscopy as novel tool for early detection of esophageal dysplasia and adenocarcinoma
Postmortem Minimally Invasive Autopsy in Critically Ill COVID-19 Patients at the Bedside: A Proof-of-Concept Study at the ICU
Proteogenomic analysis reveals RNA as a source for tumor-agnostic neoantigen identification
Microsatellite instability and sex-specific differences of survival in gastric cancer after neoadjuvant chemotherapy without and with taxane: An observational study in real world patients
Low microsatellite instability: A distinct instability type in gastric cancer?
Significant Tumor Regression after Neoadjuvant Chemotherapy in Gastric Cancer, but Poor Survival of the Patient? Role of MHC Class I Alterations
Interdisziplinäre ultraschallgesteuerte minimal-invasive Autopsie bei COVID-19-Verstorbenen auf der Intensivstation einer Universitätsklinik
Organ manifestations of COVID-19: what have we learned so far (not only) from autopsies?
Genetic alterations of the SUMO isopeptidase SENP6 drive lymphomagenesis and genetic instability in diffuse large B-cell lymphoma
PET-directed combined modality therapy for gastroesophageal junction cancer: Results of the multicentre prospective MEMORI trial of the German Cancer Consortium (DKTK)
Elevated microsatellite instability at selected tetranucleotide (<scp>EMAST</scp>) repeats in gastric cancer: a distinct microsatellite instability type with potential clinical impact?
Proteogenomic analysis reveals RNA as an important source for tumor-agnostic neoantigen identification correlating with T-cell infiltration
AXL Inhibition in Macrophages Stimulates Host-versus-Leukemia Immunity and Eradicates Naïve and Treatment-Resistant Leukemia
XIAP restrains TNF-driven intestinal inflammation and dysbiosis by promoting innate immune responses of Paneth and dendritic cells
XIAP restrains TNF-driven intestinal inflammation and dysbiosis by promoting innate immune responses of Paneth and dendritic cells.
Sexual Difference Matters: Females with High Microsatellite Instability Show Increased Survival after Neoadjuvant Chemotherapy in Gastric Cancer
MLKL promotes cellular differentiation in myeloid leukemia by facilitating the release of G-CSF
Diverse ‘just-right’ levels of chromosomal instability and their clinical implications in neoadjuvant treated gastric cancer
Correction: MLKL promotes cellular differentiation in myeloid leukemia by facilitating the release of G-CSF
Cisplatin and 5-fluorouracil with or without epidermal growth factor receptor inhibition panitumumab for patients with non-resectable, advanced or metastatic oesophageal squamous cell cancer: a prospective, open-label, randomised phase III AIO/EORTC trial (POWER)
MCL-1 gains occur with high frequency in lung adenocarcinoma and can be targeted therapeutically
CXCR4-Targeted PET Imaging of Central Nervous System B-Cell Lymphoma
Impact of Tumor Localization and Molecular Subtypes on the Prognostic and Predictive Significance of p53 Expression in Gastric Cancer
Prognostic implication of molecular subtypes and response to neoadjuvant chemotherapy in 760 gastric carcinomas: role of Epstein–Barr virus infection and high‐ and low‐microsatellite instability
PET-directed combined modality therapy for gastroesophageal junction cancer: First results of the prospective MEMORI trial.
Inhibition of PLK1 by capped‐dose volasertib exerts substantial efficacy in MDS and sAML while sparing healthy haematopoiesis
Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis
Selective inhibition of BCL-2 is a promising target in patients with high-risk myelodysplastic syndromes and adverse mutational profile
A microsatellite based multiplex PCR method for the detection of chromosomal instability in gastric cancer