Area of research
Genetics · Pulmonary and Respiratory Medicine
Research interest
Research interests include Glioma Diagnosis and Treatment, Sarcoma Diagnosis and Treatment, Genomic variations and chromosomal abnormalities, and Cancer-related Molecular Pathways.
Centrosome protein TAX1BP2 mediates STING-dependent immune response and potentiates anti-PD-1 efficacy in hepatocellular carcinoma.
TEC kinase stabilizes PLK4 to promote liver cancer metastasis
Centrosomal protein TAX1BP2 inhibits centrosome-microtubules aberrations induced by hepatitis B virus X oncoprotein.
Survival and prognosis with osteosarcoma: outcomes in more than 2000 patients in the EURAMOS-1 (European and American Osteosarcoma Study) cohort
Comparison of MAPIE versus MAP in patients with a poor response to preoperative chemotherapy for newly diagnosed high-grade osteosarcoma (EURAMOS-1): an open-label, international, randomised controlled trial
History of chickenpox in glioma risk: a report from the glioma international case–control study (<scp>GICC</scp>)
Current state of pediatric sarcoma biology and opportunities for future discovery: A report from the sarcoma translational research workshop
NKD2, a negative regulator of Wnt signaling, suppresses tumor growth and metastasis in osteosarcoma
Comprehensive Genomic Analysis Identifies Novel Subtypes and Targets of Triple-Negative Breast Cancer
EURAMOS-1, an international randomised study for osteosarcoma: results from pre-randomisation treatment
Germline Mutations in Shelterin Complex Genes Are Associated With Familial Glioma
Novel somatic and germline mutations in intracranial germ cell tumours
CNS-PNETs with C19MC amplification and/or LIN28 expression comprise a distinct histogenetic diagnostic and therapeutic entity
A gene signature based method for identifying subtypes and subtype-specific drivers in cancer with an application to medulloblastoma
The Narrow-Spectrum HDAC Inhibitor Entinostat Enhances NKG2D Expression Without NK Cell Toxicity, Leading to Enhanced Recognition of Cancer Cells
Intravenous injection of oncolytic picornavirus SVV-001 prolongs animal survival in a panel of primary tumor–based orthotopic xenograft mouse models of pediatric glioma
Low penetrance susceptibility to glioma is caused by the TP53 variant rs78378222
Description of selected characteristics of familial glioma patients – Results from the Gliogene Consortium
Insight in glioma susceptibility through an analysis of 6p22.3, 12p13.33-12.1, 17q22-23.2 and 18q23 SNP genotypes in familial and non-familial glioma