Ariana Peck — California Institute of Technology

Area of research

Structural Biology · Materials Chemistry

Research interest

Research focused on MAPK/ERK pathway and KRAS, with related work in Cancer research, Immunology, Benchmarking. Notable publications include 'Mechanism of MEK inhibition determines efficacy in mutant KRAS- versus BRAF-driven cancers', 'Structure of the BRAF-MEK Complex Reveals a Kinase Activity Independent Role for BRAF in MAPK Signaling', and 'Engineering a Single-Agent Cytokine/Antibody Fusion That Selectively Expands Regulatory T Cells for Autoimmune Disease Therapy'.

Recent publications

A realistic phantom dataset for benchmarking cryo-ET data annotation

Nature Methods 2025cited by 6position: firstdoi

Engineering a Single-Agent Cytokine/Antibody Fusion That Selectively Expands Regulatory T Cells for Autoimmune Disease Therapy

The Journal of Immunology 2018cited by 66position: middledoi

Structure of the BRAF-MEK Complex Reveals a Kinase Activity Independent Role for BRAF in MAPK Signaling

Cancer Cell 2014cited by 253position: middledoi

Mechanism of MEK inhibition determines efficacy in mutant KRAS- versus BRAF-driven cancers

Nature 2013cited by 320position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Jacob R. Haling · Genomics Institute of the Novartis Research Foundation2 papers (2013–2014)Shiva Malek · Yale Cancer Center2 papers (2013–2014)David A. Agard · Quantitative BioSciences1 papers (2025–2025)Kyung Song · Case Western Reserve University1 papers (2013–2013)Tony Morales · Loxo Oncology at Lilly (United States)1 papers (2014–2014)Jamie B. Spangler · Bloomberg (United States)1 papers (2018–2018)— · 1 papers (2013–2013)Daniel Serwas · University of California, Berkeley1 papers (2025–2025)— · 1 papers (2025–2025)Feng Wang · Shenyang University of Technology1 papers (2025–2025)— · 1 papers (2025–2025)Tracy A. Young · University of Glasgow1 papers (2018–2018)Lori S. Friedman · KU Leuven1 papers (2013–2013)— · 1 papers (2014–2014)— · 1 papers (2014–2014)Eleonora Trotta · Integrated BioTherapeutics (United States)1 papers (2018–2018)Christine Orr · Queen's University1 papers (2013–2013)— · 1 papers (2013–2013)Mohammadreza Paraan · Florida State University1 papers (2025–2025)— · 1 papers (2018–2018)

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