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Tomas Hökfelt

Karolinska Institutet · SE
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Area of research
Cellular and Molecular Neuroscience · Molecular Biology
Research interest
Dr. Tomas Hokfelt, M.D., Ph.D., is the Member of Scientific Advisory Board at Neurome, Inc. Dr. Hokfelt, a Professor in the Department of Neuroscience at Karolinska Institutet in Stockholm, Sweden, is a world leader in the mapping of chemical components in neurotransmission in the brain. He pursued his undergraduate medical studies at Karolinska Institutet, where he also earned his Ph.D. and M.D. In 1969, he was appointed assistant professor at the Swedish Medical Research Council. In 1979, Dr. Hökfelt became Professor in Histology with Cell Biology at Karolinska Institutet and he served as the vice chairman of its Department of Neuroscience from 1993-1999. Dr.
h-index
163
citations
104,487
works
1,243
NIH funding
primary concept
Medicine
email

Recent publications

Cholesterol modulates trafficking of galanin receptor subtype 1 but not subtype 2: Insights from live-cell imaging.
2026cited by 0position: contributordoi
Neural ensembles that encode nocifensive mechanical and heat pain in mouse spinal cord
Nature Neuroscience 2025cited by 15position: middledoi
Neural ensembles that encode nocifensive mechanical and heat pain in mouse spinal cord.
2025cited by 7position: contributordoi
Substance P, NPY, CCK and their receptors in five brain regions in major depressive disorder with transcriptomic analysis of locus coeruleus neurons
European Neuropsychopharmacology 2024cited by 15position: contributordoi
Transient expression of the neuropeptide galanin modulates peripheral‑to‑central connectivity in the somatosensory thalamus during whisker development in mice.
2024cited by 8position: contributordoi
A hydrophobic groove in secretagogin allows for alternate interactions with SNAP-25 and syntaxin-4 in endocrine tissues.
2024cited by 2position: contributordoi
Concerted transcriptional regulation of the morphogenesis of hypothalamic neurons by ONECUT3.
2024cited by 2position: contributordoi
Neuronal diversity of neuropeptide signaling, including galanin, in the mouse locus coeruleus
Proceedings of the National Academy of Sciences 2023cited by 33position: lastdoi
Neuronal diversity of neuropeptide signaling, including galanin, in the mouse locus coeruleus.
2023cited by 28position: contributordoi
Spatiotemporal characterization of cellular tau pathology in the human locus coeruleus–pericoerulear complex by three-dimensional imaging
Acta Neuropathologica 2022cited by 64position: middledoi
The neuropeptide landscape of human prefrontal cortex
Proceedings of the National Academy of Sciences 2022cited by 53position: lastdoi
The neuropeptide landscape of human prefrontal cortex.
2022cited by 48position: contributordoi
Ontogenetic rules for the molecular diversification of hypothalamic neurons.
2022cited by 21position: contributordoi
Expression of substance P, NPY and their Receptors Is Altered in Major Depression
2022cited by 7position: contributordoi
Genome-wide single cell annotation of the human protein-coding genes
2022cited by 2position: contributordoi
Disorganization and degeneration of liver sympathetic innervations in nonalcoholic fatty liver disease revealed by 3D imaging
Science Advances 2021cited by 96position: lastdoi
Involvement of Scratch2 in GalR1-mediated depression-like behaviors in the rat ventral periaqueductal gray.
2021cited by 5position: contributordoi
An atlas of the protein-coding genes in the human, pig, and mouse brain
Science 2020cited by 1,174position: middledoi
Molecular design of hypothalamus development
Nature 2020cited by 173position: middledoi
Expression and regulation of FRMD6 in mouse DRG neurons and spinal cord after nerve injury
Scientific Reports 2020cited by 7position: middledoi
On the origin of eating disorders: altered signaling between gut microbiota, adaptive immunity and the brain melanocortin system regulating feeding behavior
Current Opinion in Pharmacology 2019cited by 81position: lastdoi
SNAP-25 isoforms differentially regulate synaptic transmission and long-term synaptic plasticity at central synapses
Scientific Reports 2019cited by 64position: middledoi
Facilitation of neuropathic pain by the NPY Y1 receptor-expressing subpopulation of excitatory interneurons in the dorsal horn
Scientific Reports 2019cited by 60position: middledoi
A preliminary study on DRGs and spinal cord of a galanin receptor 2-EGFP transgenic mouse
Neuropeptides 2019cited by 8position: middledoi
Neuropeptide and Small Transmitter Coexistence: Fundamental Studies and Relevance to Mental Illness
Frontiers in Neural Circuits 2018cited by 142position: firstdoi
Exploring the transcriptome of resident spinal microglia after collagen antibody–induced arthritis
Pain 2018cited by 60position: middledoi
Significance of risk polymorphisms for depression depends on stress exposure
Scientific Reports 2018cited by 59position: middledoi
miR-183 cluster scales mechanical pain sensitivity by regulating basal and neuropathic pain genes
Science 2017cited by 143position: middledoi
A <scp>TRPV</scp> 1‐to‐secretagogin regulatory axis controls pancreatic β‐cell survival by modulating protein turnover
The EMBO Journal 2017cited by 66position: middledoi
Molecular interrogation of hypothalamic organization reveals distinct dopamine neuronal subtypes
Nature Neuroscience 2016cited by 533position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

· 11 papers (2021–2026)Tibor Harkany · Karolinska Institutet9 papers (2014–2023)Jan Mulder · Science for Life Laboratory9 papers (2013–2022)Mathias Uhlén · Science for Life Laboratory7 papers (2014–2022)Swapnali Barde · Linköping University6 papers (2013–2022)Tibor Harkany · Institute for Biomedicine5 papers (2022–2024)Mingdong Zhang · Xinjiang Medical University5 papers (2012–2025)Miklós Palkovits · Tulane University4 papers (2013–2022) · 4 papers (2014–2018)Qing Xu · Capital Medical University4 papers (2014–2023)Roman A. Romanov · Medical University of Vienna4 papers (2014–2023)Csaba Ádori · Karolinska Institutet4 papers (2014–2022)Tiejun Shi · Harbin Institute of Technology3 papers (2012–2020)J.F.W. Deakin · University of Manchester3 papers (2014–2018)Jie Su · Karolinska Institutet3 papers (2018–2025)Nicholas Mitsios · Karolinska Institutet3 papers (2014–2022)Gabriella Juhász · University of Manchester3 papers (2014–2018)Erik Keimpema · Medical University of Vienna2 papers (2015–2020)Martin Häring · Karolinska Institutet2 papers (2017–2020)Ján Kehr · Statistics Sweden2 papers (2018–2021)
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