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Stéphanie Debette

Centre National de la Recherche Scientifique · FR
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Area of research
Genetics · Neurology
Research interest
Research interests include Genetic Associations and Epidemiology, Dementia and Cognitive Impairment Research, Acute Ischemic Stroke Management, and Cerebrovascular and genetic disorders.
h-index
94
citations
42,505
works
523
NIH funding
primary concept
email

Recent publications

ABSTRACT NUMBER: ESOC2026A2044 CONTEXT-DEPENDENT PQTLS REVEAL BLOOD PRESSURE–SPECIFIC MOLECULAR MECHANISMS LINKED TO VASCULAR BRAIN DISEASES
European Stroke Journal 2026cited by 0position: middledoi
Direct oral anticoagulants versus no anticoagulation for the prevention of stroke in survivors of intracerebral haemorrhage with atrial fibrillation (PRESTIGE-AF): a multicentre, open-label, randomised, phase 3 trial
The Lancet 2025cited by 37position: middledoi
Machine learning in Alzheimer’s disease genetics
Nature Communications 2025cited by 8position: middledoi
Molecular determinants of thrombosis recurrence risk across venous thromboembolism subtypes
Blood 2025cited by 7position: middledoi
The brain neurovascular epigenome and its association with dementia
Neuron 2025cited by 5position: middledoi
Burden of intracerebral haemorrhage in Europe: forecasting incidence and mortality between 2019 and 2050
The Lancet Regional Health - Europe 2024cited by 67position: middledoi
Genetic Complexities of Cerebral Small Vessel Disease, Blood Pressure, and Dementia
JAMA Network Open 2024cited by 19position: lastdoi
Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries
Nature Genetics 2024cited by 17position: middledoi
Genetic risk factors underlying white matter hyperintensities and cortical atrophy
Nature Communications 2024cited by 14position: middledoi
Cohort Profile: Dementia Risk Prediction Project (DRPP)
International Journal of Epidemiology 2024cited by 2position: middledoi
Neuroimaging standards for research into small vessel disease—advances since 2013
The Lancet Neurology 2023cited by 926position: middledoi
Genomics of perivascular space burden unravels early mechanisms of cerebral small vessel disease
Nature Medicine 2023cited by 120position: lastdoi
Genetic Associations Between Modifiable Risk Factors and Alzheimer Disease
JAMA Network Open 2023cited by 92position: middledoi
Genome-wide association meta-analysis of spontaneous coronary artery dissection identifies risk variants and genes related to artery integrity and tissue-mediated coagulation
Nature Genetics 2023cited by 85position: middledoi
Large multi-ethnic genetic analyses of amyloid imaging identify new genes for Alzheimer disease
Acta Neuropathologica Communications 2023cited by 52position: middledoi
Multiancestry analysis of the HLA locus in Alzheimer’s and Parkinson’s diseases uncovers a shared adaptive immune response mediated by <i>HLA-DRB1*04</i> subtypes
Proceedings of the National Academy of Sciences 2023cited by 47position: middledoi
Genetic Risk Score for Intracranial Aneurysms: Prediction of Subarachnoid Hemorrhage and Role in Clinical Heterogeneity
Stroke 2023cited by 31position: middledoi
Identification of circulating proteins associated with general cognitive function among middle-aged and older adults
Communications Biology 2023cited by 21position: middledoi
Genetic Insights on the Relation of Vascular Risk Factors and Cervical Artery Dissection
Journal of the American College of Cardiology 2023cited by 19position: lastdoi
New insights into the genetic etiology of Alzheimer’s disease and related dementias
Nature Genetics 2022cited by 2,415position: middledoi
Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer’s disease
Nature Genetics 2022cited by 213position: middledoi
Genome-wide meta-analysis for Alzheimer’s disease cerebrospinal fluid biomarkers
Acta Neuropathologica 2022cited by 135position: middledoi
Association of Rare <i>APOE</i> Missense Variants V236E and R251G With Risk of Alzheimer Disease
JAMA Neurology 2022cited by 89position: middledoi
Genome-wide association study reveals novel genetic loci: a new polygenic risk score for mitral valve prolapse
European Heart Journal 2022cited by 69position: middledoi
Genome-wide associations of aortic distensibility suggest causality for aortic aneurysms and brain white matter hyperintensities
Nature Communications 2022cited by 58position: middledoi
Meta-analysis of genome-wide association studies identifies ancestry-specific associations underlying circulating total tau levels
Communications Biology 2022cited by 38position: middledoi
Circulating Metabolome and White Matter Hyperintensities in Women and Men
Circulation 2022cited by 37position: middledoi
Stroke-associated intergenic variants modulate a human FOXF2 transcriptional enhancer
Proceedings of the National Academy of Sciences 2022cited by 18position: middledoi
Stroke genetics informs drug discovery and risk prediction across ancestries
Research Square 2022cited by 10position: firstdoi
Protective association of <i>HLA‐DRB1</i>*04 subtypes in neurodegenerative diseases implicates acetylated tau PHF6 sequences
Alzheimer s & Dementia 2022cited by 2position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Christophe Tzourio · Université de Bordeaux6 papers (2013–2019) · 5 papers (2013–2023)Sudha Seshadri · National University Heart Centre Singapore5 papers (2012–2022)Stefan T. Engelter · University of Basel5 papers (2012–2023)Alessandro Pezzini · University of Lausanne4 papers (2012–2023)Muralidharan Sargurupremraj · Institute for Neurodegenerative Disorders4 papers (2022–2025)Anna Bersano · University Hospital Heidelberg4 papers (2012–2023)Turgut Tatlisumak · University of Gothenburg3 papers (2012–2023)Tiina M. Metso · University Hospital Heidelberg3 papers (2012–2023)Jennifer J. Majersik · University of Utah3 papers (2018–2023)Emmanuel Touzé · University of Virginia3 papers (2012–2018)Philippe Amouyel · Laboratoire Epidémiologie et Analyses en Santé Publique : Risques, Maladies Chroniques et Handicaps3 papers (2013–2023)Philippe Lyrer · KU Leuven3 papers (2012–2023) · 3 papers (2013–2017)Vincent Thijs · Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico3 papers (2012–2023)Caspar Grond‐Ginsbach · Heidelberg University3 papers (2012–2023)Hugh S. Markus · Oxford Research Group3 papers (2018–2023)Didier Leys · Université de Lille3 papers (2012–2023)Alexa Beiser · Ollscoil na Gaillimhe – University of Galway3 papers (2012–2019)Armin Grau · Klinikum Ludwigshafen2 papers (2012–2013)
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