Area of research
Statistics and Probability · Management Science and Operations Research
Research interest
Research interests include Statistical Methods in Clinical Trials, Optimal Experimental Design Methods, Computational Drug Discovery Methods, and Advanced Causal Inference Techniques.
Optimal Dose and Safety of Intravenous Favipiravir in Hospitalized Patients With <scp>COVID</scp> ‐19: A Dose‐Escalating, Randomized Controlled Phase Ib Study
Modern Clinical Trials: Seamless Designs and Master Protocols
Design of platform trials with a change in the control treatment arm
Using circulating tumor DNA as a novel biomarker of efficacy for dose-finding designs in oncology
Seamless monotherapy-combination phase I dose-escalation model-based design
How to add baskets to an ongoing basket trial with information borrowing
A randomised-controlled Phase I de-escalation trial of Molnupiravir and Nirmatrelvir/Ritonavir combination for mild-moderate SARS-CoV-2 infection
Clinical and cost-effectiveness of individualised exercises and foot orthoses in the treatment of plantar heel pain: protocol for the TREADON randomised multi-arm multi-stage adaptive trial
Optimal dose and safety of intravenous favipiravir in hospitalised patients with SARS-CoV-2 infection: a Phase Ib, open-label, dose-escalating, randomised controlled study
948P Cancer Research UK first-in-human (FIH) phase I/IIa trial of the prostaglandin E2 (PGE2) receptor 4 (EP4) antagonist HTL0039732 (HTL) as monotherapy and in combination with immunotherapy in patients with advanced solid tumours
A comparison of model-free phase I dose escalation designs for dual-agent combination therapies
A Preplanned Multi‐Stage Platform Trial for Discovering Multiple Superior Treatments With Control of FWER and Power
A multi‐arm multi‐stage platform design that allows preplanned addition of arms while still controlling the family‐wise error
Bayesian model averaging for partial ordering continual reassessment methods
Early phase clinical trials in oncology: Realising the potential of seamless designs
A comparison of Bayesian information borrowing methods in basket trials and a novel proposal of modified exchangeability‐nonexchangeability method
A Bayesian multi‐arm multi‐stage clinical trial design incorporating information about treatment ordering
Determining the minimum duration of treatment in tuberculosis: An order restricted non‐inferiority trial design
Molnupiravir versus placebo in unvaccinated and vaccinated patients with early SARS-CoV-2 infection in the UK (AGILE CST-2): a randomised, placebo-controlled, double-blind, phase 2 trial
Practical implementation of the partial ordering continual reassessment method in a Phase I combination‐schedule dose‐finding trial
Bayesian sample size determination in basket trials borrowing information between subsets
A Randomised -Controlled Phase 2 trial of Molnupiravir in Unvaccinated and Vaccinated Individuals with Early SARS-CoV-2
Generalization of Cramér-Rao and Bhattacharyya inequalities for the weighted covariance matrix
Lancaster EPrints (Lancaster University) 2017cited by 3position: last
Shannon's differential entropy asymptotic analysis in a Bayesian problem
Lancaster EPrints (Lancaster University) 2015cited by 3position: last
<span>Asymptotic behaviour of the weighted Shannon differential entropy in a Bayesian problem</span>