Area of research
Physiology · Computational Theory and Mathematics
Research interest
Research focused on Neurodegeneration and Biophysics, with related work in Fibril, In vivo, Amyloid (mycology). Notable publications include 'The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes', 'The mechanism of γ‐Secretase dysfunction in familial Alzheimer disease', and 'Amyloid β Oligomers Disrupt Blood–CSF Barrier Integrity by Activating Matrix Metalloproteinases'.
Mixing Aβ(1–40) and Aβ(1–42) peptides generates unique amyloid fibrils
De novo design of a biologically active amyloid
Amyloid beta oligomers induce neuronal elasticity changes in age-dependent manner: a force spectroscopy study on living hippocampal neurons
Amyloid β Oligomers Disrupt Blood–CSF Barrier Integrity by Activating Matrix Metalloproteinases
The Alzheimer Disease Protective Mutation A2T Modulates Kinetic and Thermodynamic Properties of Amyloid-β (Aβ) Aggregation
Amyloid-β Protofibrils: Size, Morphology and Synaptotoxicity of an Engineered Mimic
The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes
The mechanism of γ‐Secretase dysfunction in familial Alzheimer disease
Neurotoxicity and Memory Deficits Induced by Soluble Low-Molecular-Weight Amyloid- 1-42 Oligomers Are Revealed In Vivo by Using a Novel Animal Model
Molecular Plasticity Regulates Oligomerization and Cytotoxicity of the Multipeptide-length Amyloid-β Peptide Pool