Area of research
Cardiology and Cardiovascular Medicine · Internal Medicine
Research interest
Research focused on ATP-binding cassette transporter and Abcg2, with related work in Tranexamic acid, Efflux, Pharmacology. Notable publications include 'Towards Optimization of Hydroxychloroquine Dosing in Intensive Care Unit COVID-19 Patients', 'Prevalence of poor biological response to clopidogrel', and 'A semi‐mechanistic absorption model to evaluate drug–drug interaction with dabigatran: application with clarithromycin'.
Tyrosine kinase inhibitors and direct oral anticoagulants: In vitro evaluation of drug–drug interaction mediated by P‐glycoprotein
Towards Optimization of Hydroxychloroquine Dosing in Intensive Care Unit COVID-19 Patients
Exposure–Response Relationship of Tranexamic Acid in Cardiac Surgery
A new paradigm for personalized prophylaxis for patients with severe haemophilia A
Pharmacokinetics for haemophilia treaters: Meaning of PK parameters, interpretation pitfalls, and use in the clinic
Pharmacological characterization of the 3D MucilAir™ nasal model
Potential usefulness of activated charcoal (DOAC remove®) for dRVVT testing in patients receiving Direct Oral AntiCoagulants
Direct oral anticoagulants are associated with limited damage of endothelial cells of the blood-brain barrier mediated by the thrombin/PAR-1 pathway
In vitro assessment of P‐gp and BCRP transporter‐mediated drug–drug interactions of riociguat with direct oral anticoagulants
Assessment of HBEC-5i endothelial cell line cultivated in astrocyte conditioned medium as a human blood-brain barrier model for ABC drug transport studies
Pharmacological Characterization of the RPMI 2650 Model as a Relevant Tool for Assessing the Permeability of Intranasal Drugs
In Vitro Comparison of the Role of P-Glycoprotein and Breast Cancer Resistance Protein on Direct Oral Anticoagulants Disposition
Intravenous Tranexamic Acid Bolus plus Infusion Is Not More Effective than a Single Bolus in Primary Hip Arthroplasty
Is RPMI 2650 a Suitable In Vitro Nasal Model for Drug Transport Studies?
Pharmacokinetic/pharmacodynamic model for unfractionated heparin dosing during cardiopulmonary bypass
Effect of Activated Charcoal on Rivaroxaban Complex Absorption
In vitro and in vivo evaluation of drug–drug interaction between dabigatran and proton pump inhibitors
Investigation of drug–drug interactions between clopidogrel and fluoxetine
Prevalence of poor biological response to clopidogrel
A semi‐mechanistic absorption model to evaluate drug–drug interaction with dabigatran: application with clarithromycin