Area of research
Neurology · Physiology
Research interest
Research interests include Neuroinflammation and Neurodegeneration Mechanisms, Alzheimer's disease research and treatments, Advanced Proteomics Techniques and Applications, and Single-cell and spatial transcriptomics.
Development, characterization, and replication of proteomic aging clocks: Analysis of 2 population-based cohorts
Organ aging signatures in the plasma proteome track health and disease
Proteomic architecture of frailty across the spectrum of cardiovascular disease
Molecular hallmarks of heterochronic parabiosis at single-cell resolution
An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging
The protein inputs of an ultra-predictive aging clock represent viable anti-aging drug targets
Author Correction: An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging
Integrating multimodal data to support Alzheimer’s disease target prioritization
Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain
A single-cell transcriptomic atlas characterizes ageing tissues in the mouse
Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer’s disease
Ageing hallmarks exhibit organ-specific temporal signatures
Physiological blood–brain transport is impaired with age by a shift in transcytosis
Data mining of human plasma proteins generates a multitude of highly predictive aging clocks that reflect different aspects of aging
Author Correction: Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain
Author Correction: Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain
Undulating changes in human plasma proteome profiles across the lifespan
Multiomics modeling of the immunome, transcriptome, microbiome, proteome and metabolome adaptations during human pregnancy
Multiple Click-Selective tRNA Synthetases Expand Mammalian Cell-Specific Proteomics
Preclinical Assessment of Young Blood Plasma for Alzheimer Disease