Area of research
Immunology · Molecular Biology
Research interest
Research interests include Immunotherapy and Immune Responses, Immune Response and Inflammation, RNA Interference and Gene Delivery, and Immune cells in cancer.
A therapeutic hepatitis B mRNA vaccine with strong immunogenicity and persistent virological suppression
Herpes zoster mRNA vaccine induces superior vaccine immunity over licensed vaccine in mice and rhesus macaques
Algorithm for optimized mRNA design improves stability and immunogenicity
Multivalent antigen display on nanoparticle immunogens increases B cell clonotype diversity and neutralization breadth to pneumoviruses
Unmodified rabies mRNA vaccine elicits high cross-neutralizing antibody titers and diverse B cell memory responses
Delayed generation of functional virus-specific circulating T follicular helper cells correlates with severe COVID-19
Functional monocytic myeloid-derived suppressor cells increase in blood but not airways and predict COVID-19 severity
Differential expansion of circulating human MDSC subsets in patients with cancer, infection and inflammation
Effects of tumour necrosis factor on cardiovascular disease and cancer: A two-sample Mendelian randomization study
Route of Vaccine Administration Alters Antigen Trafficking but Not Innate or Adaptive Immunity
A hexavalent Coxsackievirus B vaccine is highly immunogenic and has a strong protective capacity in mice and nonhuman primates
Live attenuated pertussis vaccine BPZE1 induces a broad antibody response in humans
Circulating interleukins in relation to coronary artery disease, atrial fibrillation and ischemic stroke and its subtypes: A two-sample Mendelian randomization study
Deciphering myeloid-derived suppressor cells: isolation and markers in humans, mice and non-human primates
Efficient Targeting and Activation of Antigen-Presenting Cells In Vivo after Modified mRNA Vaccine Administration in Rhesus Macaques
Neutrophils acquire the capacity for antigen presentation to memory CD4+ T cells in vitro and ex vivo
Granulocytes: New Members of the Antigen-Presenting Cell Family
Induction of Robust B Cell Responses after Influenza mRNA Vaccination Is Accompanied by Circulating Hemagglutinin-Specific ICOS+ PD-1+ CXCR3+ T Follicular Helper Cells
Matrix Metalloproteinase Responsive Nanoparticles for Synergistic Treatment of Colorectal Cancer via Simultaneous Anti-Angiogenesis and Chemotherapy