Area of research
Molecular Biology · Hematology
Research interest
Research focused on RNA splicing and Minigene, with related work in Exon, Exon skipping, Somatic cell. Notable publications include 'Predictive value of blood eosinophils and exhaled nitric oxide in adults with mild asthma: a prespecified subgroup analysis of an open-label, parallel-group, randomised controlled...', 'Regulation of a strong F9 cryptic 5′ss by intrinsic elements and by combination of tailored U1snRNAs with antisense oligonucleotides', and 'An Exon-Specific U1snRNA Induces a Robust Factor IX Activity in Mice Expressing Multiple Human FIX Splicing Mutants'.
Predictive value of blood eosinophils and exhaled nitric oxide in adults with mild asthma: a prespecified subgroup analysis of an open-label, parallel-group, randomised controlled trial
A Compensatory U1snRNA Partially Rescues FAH Splicing and Protein Expression in a Splicing-Defective Mouse Model of Tyrosinemia Type I
Disease-causing variants of the conserved +2T of 5′ splice sites can be rescued by engineered U1snRNAs
The somatic FAH C.1061C>A change counteracts the frequent FAH c.1062+5G>A mutation and permits U1snRNA-based splicing correction
An Exon-Specific U1snRNA Induces a Robust Factor IX Activity in Mice Expressing Multiple Human FIX Splicing Mutants
Exploring Splicing-Switching Molecules For Seckel Syndrome Therapy
Regulation of a strong<i>F9</i>cryptic 5′ss by intrinsic elements and by combination of tailored U1snRNAs with antisense oligonucleotides