Area of research
Cardiology and Cardiovascular Medicine · Molecular Biology
Research interest
Research interests include Cardiovascular Function and Risk Factors, Heart Failure Treatment and Management, Angiogenesis and VEGF in Cancer, and Nitric Oxide and Endothelin Effects.
PIEZO Force Sensors and the Heart.
Cardiovascular involvement in glycogen storage diseases.
Analysis of the diabetic arterial transcriptome to define novel biomarkers of macrovascular disease
Prevalence and incidence of left ventricular systolic dysfunction and adverse outcomes in patients receiving
<i>de novo</i>
and replacement pacemaker therapy for bradycardia
Characterisation of diabetes-associated adipose tissue dysfunction across the spectrum of body mass index
<i>PIEZO1</i> variant implications for biological understanding and human health.
Application of CIBERSORTx and BayesPrism to deconvolution of bulk RNA-seq data from human myocardium and skeletal muscle.
Endothelial insulin-like growth factor-1 signalling regulates vascular barrier function and atherogenesis.
Paracrine role of endothelial IGF-1 receptor in depot-specific adipose tissue adaptation in male mice.
Comorbidity trajectories before and after the diagnosis of heart failure: A UK Biobank cohort study.
Infection in people with heart failure: an overlooked cause of adverse outcomes.
Assessing LV Contractility Identifies Populations With Preserved Ejection Fraction at Risk of Adverse Heart Failure Outcomes.
Navigating UK cardiology higher specialty training applications: a practical guide.
Clinical and cardiovascular magnetic resonance factors associated with elevated neutrophil-to-lymphocyte ratio in patients with heart failure: an analysis of a single-centre, prospective registry.
Widening gap in life expectancy between patients with heart failure living in most and least deprived areas: a longitudinal cohort study.
Murine limb ischaemia induces structural and functional remodelling of local and distant bone marrow
Murine limb ischaemia induces structural and functional remodelling of local and distant bone marrow
Advancing the access to cardiovascular diagnosis and treatment among women with cardiovascular disease: a joint British Cardiovascular Societies’ consensus document
Advancing the access to cardiovascular diagnosis and treatment among women with cardiovascular disease: a joint British Cardiovascular Societies' consensus document.
The diabetic myocardial transcriptome reveals Erbb3 and Hspa2 as a novel biomarkers of incident heart failure.
Inflammation, infection, and cardiovascular risk.
Diabetes mellitus does not alter mortality or hospitalisation risk in patients with newly diagnosed heart failure with preserved ejection fraction: Time to rethink pathophysiological models of disease progression.
Small molecule modulation of insulin receptor-insulin like growth factor-1 receptor heterodimers in human endothelial cells.
Echocardiographic screening for heart failure and optimization of the care pathway for individuals with pacemakers: a randomized controlled trial.
Insulin receptor signalling in PDGFRβ-expressing cells influences systemic metabolism and negatively impacts lipid storage.
Comorbidity trajectories before and after the diagnosis of heart failure: a UK Biobank cohort study
Distinct, common and synergistic effects of insulin and IGF-1 receptors on healthy murine ageing.
Small molecule modulation of insulin receptor-insulin like growth factor-1 receptor heterodimers in human endothelial cells
Studying Adipose Endothelial Cell/Adipocyte Cross-Talk in Human Subcutaneous Adipose Tissue.
The diabetic myocardial transcriptome reveals Erbb3 as a novel biomarker of incident heart failure