Area of research
Immunology · Pulmonary and Respiratory Medicine
Research interest
Research interests include Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis, Immune Cell Function and Interaction, Virology and Viral Diseases, and T-cell and B-cell Immunology.
LOXL4, but not LOXL2, is the critical determinant of pathological collagen cross-linking and fibrosis in the lung
LOXL4, but not LOXL2, is the critical determinant of pathological collagen cross-linking and fibrosis in the lung.
Inhibition of MRTF activation as a clinically achievable anti-fibrotic mechanism for pirfenidone.
Obligate role for Rock1 and Rock2 in adult stem cell viability and function.
A WISP1 antibody inhibits MRTF signaling to prevent the progression of established liver fibrosis
Inhibition of MRTF activation as a clinically achievable anti-fibrotic mechanism for pirfenidone
BMP1 is not required for lung fibrosis in mice
TGFβ2 and TGFβ3 isoforms drive fibrotic disease pathogenesis
TGFβ2 and TGFβ3 isoforms drive fibrotic disease pathogenesis.
Integration of eQTL and a Single-Cell Atlas in the Human Eye Identifies Causal Genes for Age-Related Macular Degeneration
Neutrophil serine protease 4 is required for mast cell-dependent vascular leakage.
RIP1 inhibition blocks inflammatory diseases but not tumor growth or metastases
Regulation of Tumor-Associated Myeloid Cell Activity by CBP/EP300 Bromodomain Modulation of H3K27 Acetylation
Tumor suppressor BAP1 is essential for thymic development and proliferative responses of T lymphocytes
Heterogeneous gene expression signatures correspond to distinct lung pathologies and biomarkers of disease severity in idiopathic pulmonary fibrosis
Blockade of CSF-1 and IL-34 in mouse model of inflammatory arthritis and colitis show a pathogenic role for IL-34 (P5160)
Replacement of Sϵ with Sμ reveals novel mechanistic insights into rearrangements of the IgH locus and cMyc chromosomal translocations (P1400)
Critical role of activation induced cytidine deaminase in Experimental Autoimmune Encephalomyelitis