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Gianni Binotto

University of Padua · IT
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Area of research
Hematology · Genetics
Research interest
Research focused on Myeloid leukemia and Discontinuation, with related work in Ruxolitinib, Sanger sequencing, Myelofibrosis. Notable publications include 'Cobalamin Deficiency: Clinical Picture and Radiological Findings', 'Unraveling the complexity of tyrosine kinase inhibitor–resistant populations by ultra-deep sequencing of the BCR-ABL kinase domain', and 'Life after ruxolitinib: Reasons for discontinuation, impact of disease phase, and outcomes in 218 patients with myelofibrosis'.
h-index
citations
2,186
works
83
NIH funding
primary concept
email

Recent publications

Survival and quality‐of‐life implications of cytopenia trajectories in ruxolitinib‐treated myelofibrosis
Cancer 2026cited by 0position: middledoi
Dosing and clinical outcomes of ruxolitinib in patients with myelofibrosis in a real‐world setting: Interim results of the Italian observational study (ROMEI)
Cancer 2025cited by 10position: middledoi
Real‐World Efficacy Profile of Compassionate Use of Asciminib in an Italian, Multi‐Resistant Chronic‐Phase Chronic Myeloid Leukemia (CML‐CP) Patient Population
Hematological Oncology 2025cited by 5position: middledoi
Revised “iRR6” model in intermediate‐1 risk myelofibrosis patients treated with ruxolitinib
Cancer 2025cited by 5position: middledoi
Disease Phenotype Significantly Influences the Outcome After Discontinuation of Ruxolitinib in Chronic Phase Myelofibrosis
Clinical Lymphoma Myeloma & Leukemia 2025cited by 3position: middledoi
Impact of calreticulin mutations on treatment and survival outcomes in myelofibrosis during ruxolitinib therapy
Annals of Hematology 2025cited by 2position: middledoi
Nilotinib versus imatinib with early switch from imatinib to nilotinib to obtain treatment-free remission in newly diagnosed chronic myeloid leukemia patients: the analysis of the first co-primary endpoint
Leukemia 2025cited by 1position: middledoi
Cytopenias and Large Splenomegaly are Main Drivers of Poor Outcome after Discontinuation of Ruxolitinib in Chronic Phase Myelofibrosis
SSRN Electronic Journal 2025cited by 0position: middledoi
International, prospective study comparing nilotinib versus imatinib with early switch to nilotinib to obtain sustained treatment-free remission (TFR) in patients with chronic myeloid leukemia: The tfr rate at the end of follow-up
Blood 2025cited by 0position: middledoi
Prognostic impact of persistent and treatment-emergent cytopenia in 879 myelofibrosis patients treated with ruxolitinib: The “RUX-MF” study
Blood 2025cited by 0position: middledoi
Clinical outcomes of ruxolitinib treatment in 595 intermediate‐1 risk patients with myelofibrosis: The RUX‐MF Real‐World Study
Cancer 2024cited by 10position: middledoi
Personalized Transplant Decision Making for Myelofibrosis in the Era of Molecular Genetics and JAK Inhibition
Blood 2024cited by 3position: middledoi
Choice of Frontline Tyrosine‐Kinase Inhibitor and Early Events in Very Elderly Patients With Chronic Myeloid Leukemia in Chronic Phase: A “Campus <scp>CML</scp>” Study
European Journal Of Haematology 2024cited by 3position: middledoi
Baseline Features, Treatment Choice and Early Frontline TKI Permanent Discontinuation in Patients with Newly Diagnosed Chronic Myeloid Leukemia Aged 50 - 60 Years: A “Campus CML” Study
Blood 2024cited by 0position: middledoi
Cytopenias and Failure to Use Innovative Therapy Are Main Drivers of Worse Outcome after Discontinuation of Ruxolitinib in Myelofibrosis
Blood 2024cited by 0position: middledoi
Ruxolitinib in cytopenic myelofibrosis: Response, toxicity, drug discontinuation, and outcome
Cancer 2023cited by 40position: middledoi
Incidence of blast phase in myelofibrosis patients according to anemia severity at ruxolitinib start and during therapy
Cancer 2023cited by 16position: middledoi
Predictors of Response to Hydroxyurea and Switch to Ruxolitinib in HU-Resistant Polycythaemia VERA Patients: A Real-World PV-NET Study
Cancers 2023cited by 13position: middledoi
A Prognostic Model to Predict Ruxolitinib Discontinuation and Death in Patients with Myelofibrosis
Cancers 2023cited by 8position: middledoi
Determinants of frontline tyrosine kinase inhibitor choice for patients with chronic‐phase chronic myeloid leukemia: A study from the Registro Italiano LMC and Campus CML
Cancer 2023cited by 7position: middledoi
International, Prospective Study Comparing Nilotinib Versus Imatinib with Early Switch to Nilotinib to Obtain Sustained Treatment-Free Remission in Patients with Chronic Myeloid Leukemia (SUSTRENIM trial): Analysis of the Eligibility to Treatment Discontinuation
Blood 2023cited by 3position: middledoi
Determinants of Covid19 disease and of survival after Covid19 in MPN patients treated with ruxolitinib
Blood Cancer Journal 2023cited by 0position: middledoi
P1028: MYELOFIBROSIS (MF) TREATED WITH RUXOLITINIB (RUX) MONOTHERAPY: PREDICTORS OF EARLY DISCONTINUATION AND DEATH ON TREATMENT. THE SHORT-TERM RUX PROGNOSTIC MODEL (STR-PM)
HemaSphere 2023cited by 0position: middledoi
Baseline Features, Treatment Choice and Early Frontline TKI Permanent Discontinuation in Younger Patients with Chronic Myeloid Leukemia: A “Campus CML” Study
Blood 2023cited by 0position: middledoi
Efficacy of Frontline Treatment with Initial Low-Dose Tyrosine-Kinase Inhibitors in Elderly Patients with Chronic Myeloid Leukemia: A “Campus CML” Study
Blood 2023cited by 0position: middledoi
Hypocellular myelodysplastic syndromes (h-MDS): from clinical description to immunological characterization in the Italian multi-center experience
Leukemia 2022cited by 22position: middledoi
Permanent Discontinuation of Tyrosine Kinase Inhibitor Frontline Therapy in Patients with Chronic Phase Chronic Myeloid Leukemia Patients during the First 36 Months of Treatment: A "Campus CML" Study
Blood 2022cited by 2position: middledoi
S156: INTERNATIONAL, PROSPECTIVE STUDY COMPARING NILOTINIB VERSUS IMATINIB WITH EARLY SWITCH TO NILOTINIB TO OBTAIN SUSTAINED TREATMENT-FREE REMISSION IN PATIENTS WITH WITH CHRONIC MYELOID LEUKEMIA
HemaSphere 2022cited by 2position: middledoi
Ruxolitinib discontinuation syndrome: incidence, risk factors, and management in 251 patients with myelofibrosis
Blood Cancer Journal 2021cited by 74position: middledoi
Targeting Chronic Myeloid Leukemia Stem/Progenitor Cells Using Venetoclax-Loaded Immunoliposome
Cancers 2021cited by 31position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

· 8 papers (2016–2025) · 8 papers (2016–2025)Massimiliano Bonifacio · University of Naples Federico II7 papers (2017–2025)Alessandra Iurlo · Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico6 papers (2019–2025) · 6 papers (2017–2025) · 5 papers (2017–2025) · 5 papers (2019–2025) · 4 papers (2017–2021)Francesca Palandri · Bristol-Myers Squibb (Switzerland)4 papers (2013–2025)Giuseppe Saglio · Department of Public Health4 papers (2016–2022) · 4 papers (2013–2019) · 4 papers (2016–2021)Florian H. Heidel · Medizinische Hochschule Hannover3 papers (2017–2025) · 3 papers (2018–2020) · 3 papers (2017–2025)Gianantonio Rosti · Policlinico S.Orsola-Malpighi3 papers (2013–2019)Giulia Benevolo · Azienda Ospedaliera Citta' della Salute e della Scienza di Torino3 papers (2017–2025)Francesco Cavazzini · University of Padua3 papers (2017–2022) · 3 papers (2013–2018) · 3 papers (2017–2025)
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