Area of research
Molecular Biology · Neurology
Research interest
Research interests include Coenzyme Q10 studies and effects, Advancements in Battery Materials, Parkinson's Disease Mechanisms and Treatments, and Mitochondrial Function and Pathology.
The role of mitochondrial dysfunction in Alzheimer's disease pathogenesis
Altered succinylation of mitochondrial proteins, APP and tau in Alzheimer’s disease
Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing
PGC-1α, Sirtuins and PARPs in Huntington’s Disease and Other Neurodegenerative Conditions: NAD+ to Rule Them All
Rewiring of Glutamine Metabolism Is a Bioenergetic Adaptation of Human Cells with Mitochondrial DNA Mutations
Benfotiamine treatment activates the Nrf2/ARE pathway and is neuroprotective in a transgenic mouse model of tauopathy
Aberrant regulation of the GSK‐3β/NRF2 axis unveils a novel therapy for adrenoleukodystrophy
Mitochondrial dysfunction in Parkinson's disease
Distinct Nrf2 Signaling Mechanisms of Fumaric Acid Esters and Their Role in Neuroprotection against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Induced Experimental Parkinson's-Like Disease
Mutant Profilin1 transgenic mice recapitulate cardinal features of motor neuron disease
Preferential PPAR-α activation reduces neuroinflammation, and blocks neurodegeneration<i>in vivo</i>
A Randomized Clinical Trial of High-Dosage Coenzyme Q10 in Early Parkinson Disease
Inosine to Increase Serum and Cerebrospinal Fluid Urate in Parkinson Disease
Methylene blue upregulates Nrf2/ARE genes and prevents tau-related neurotoxicity
Mitochondrial Diseases of the Brain
PGC-1α, mitochondrial dysfunction, and Huntington's disease
Nitration of Hsp90 induces cell death
A role of mitochondrial complex II defects in genetic models of Huntington's disease expressing N-terminal fragments of mutant huntingtin
Usefulness of Proton and Phosphorus MR Spectroscopic Imaging for Early Diagnosis of Parkinson's Disease
Mitochondrial Dysfunction in Neurodegenerative Diseases
Impaired mitochondrial function in psychiatric disorders
Targeting Nrf2-Mediated Gene Transcription by Extremely Potent Synthetic Triterpenoids Attenuate Dopaminergic Neurotoxicity in the MPTP Mouse Model of Parkinson's Disease
Neuroprotection by cyclodextrin in cell and mouse models of Alzheimer disease
Mitochondria targeted therapeutic approaches in Parkinson's and Huntington's diseases
Somatic mitochondrial DNA mutations in early parkinson and incidental lewy body disease
Transducer of regulated CREB-binding proteins (TORCs) transcription and function is impaired in Huntington's disease