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Christoph Kuppe

Czech Academy of Sciences, Institute of Experimental Medicine · DE
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Area of research
Molecular Biology · Nephrology
Research interest
Research interests include Single-cell and spatial transcriptomics, Renal Diseases and Glomerulopathies, Chronic Kidney Disease and Diabetes, and Renal and related cancers.
h-index
36
citations
5,624
works
158
NIH funding
primary concept
Medicine
email

Recent publications

2D, or not 2D? Investigating Vertical Signal Integrity of Tissue Slices
bioRxiv (Cold Spring Harbor Laboratory) 2025cited by 7position: middledoi
Beyond benchmarking: an expert-guided consensus approach to spatially aware clustering
bioRxiv (Cold Spring Harbor Laboratory) 2025cited by 3position: middledoi
161P NECTIN4 amplification (amp) as an actionable alteration in non-small cell lung cancer (NSCLC)
Annals of Oncology 2025cited by 0position: middledoi
A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models
Nature Biotechnology 2024cited by 259position: middledoi
<i>NECTIN4</i> Amplification Is Frequent in Solid Tumors and Predicts Enfortumab Vedotin Response in Metastatic Urothelial Cancer
Journal of Clinical Oncology 2024cited by 104position: middledoi
Defining cardiac functional recovery in end-stage heart failure at single-cell resolution
Nature Cardiovascular Research 2023cited by 72position: middledoi
Spatial multi-omic map of human myocardial infarction
Nature 2022cited by 660position: firstdoi
SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids
Cell stem cell 2021cited by 265position: middledoi
Deficiency of myeloid PHD proteins aggravates atherogenesis via macrophage apoptosis and paracrine fibrotic signalling
Cardiovascular Research 2021cited by 38position: middledoi
Decoding myofibroblast origins in human kidney fibrosis
Nature 2020cited by 725position: firstdoi
Heterogeneous bone-marrow stromal progenitors drive myelofibrosis via a druggable alarmin axis
Cell stem cell 2020cited by 168position: middledoi
Novel parietal epithelial cell subpopulations contribute to focal segmental glomerulosclerosis and glomerular tip lesions
Kidney International 2019cited by 74position: firstdoi
Heterogeneity and plasticity in healthy and atherosclerotic vasculature explored by single-cell sequencing
Cardiovascular Research 2019cited by 56position: middledoi
A Functional Landscape of CKD Entities From Public Transcriptomic Data
Kidney International Reports 2019cited by 41position: middledoi
Adventitial MSC-like Cells Are Progenitors of Vascular Smooth Muscle Cells and Drive Vascular Calcification in Chronic Kidney Disease
Cell stem cell 2016cited by 297position: middledoi
Investigations of Glucocorticoid Action in GN
Journal of the American Society of Nephrology 2016cited by 48position: firstdoi
Common histological patterns in glomerular epithelial cells in secondary focal segmental glomerulosclerosis
Kidney International 2015cited by 71position: firstdoi
SP048UNRAVELING THE MECHANISM OF ACTION OF GLUCOCORTICOIDS IN GLOMERULONEPHRITIS
Nephrology Dialysis Transplantation 2015cited by 1position: firstdoi

Grants

No grants ingested yet.

Frequent collaborators

Rafael Kramann · Netherlands School of Public Administration6 papers (2016–2023)Jürgen Floege · University of Hong Kong4 papers (2015–2019)Hermann-J. Gröne · German Cancer Research Center4 papers (2015–2019) · 4 papers (2015–2019) · 4 papers (2015–2019)Peter Boor · RWTH Aachen University3 papers (2015–2020) · 2 papers (2016–2019)Nazanin Kabgani · RWTH Aachen University2 papers (2016–2019)Julio Sáez-Rodríguez · European Bioinformatics Institute2 papers (2019–2021)Brian Long · Seattle University2 papers (2025–2025) · 2 papers (2025–2025)Roland Eils · University of Michigan2 papers (2025–2025) · 2 papers (2019–2021)Naveed Ishaque · Heidelberg University2 papers (2025–2025)Judith C. Sluimer · New York University2 papers (2019–2021) · 2 papers (2015–2015)Niklas Müller‐Bötticher · Berlin Institute of Health at Charité - Universitätsmedizin Berlin2 papers (2025–2025)Rebekka K. Schneider · Harvard University2 papers (2016–2020) · 1 papers (2025–2025) · 1 papers (2025–2025)
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