Area of research
Molecular Biology · Developmental Neuroscience
Research interest
Research focused on Neurodegeneration and Neuroscience, with related work in Amyotrophic lateral sclerosis, Induced pluripotent stem cell, Organoid. Notable publications include 'Modeling Parkinson’s disease in midbrain-like organoids', 'Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation', and '4-Aminopyridine Induced Activity Rescues Hypoexcitable Motor Neurons from Amyotrophic Lateral Sclerosis Patient-Derived Induced Pluripotent Stem Cells'.
Modeling Parkinson’s disease in midbrain-like organoids
Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation
SLP-2 interacts with Parkin in mitochondria and prevents mitochondrial dysfunction in Parkin-deficient human iPSC-derived neurons and<i>Drosophila</i>
4-Aminopyridine Induced Activity Rescues Hypoexcitable Motor Neurons from Amyotrophic Lateral Sclerosis Patient-Derived Induced Pluripotent Stem Cells
Neuronal Dysfunction in iPSC-Derived Medium Spiny Neurons from Chorea-Acanthocytosis Patients Is Reversed by Src Kinase Inhibition and F-Actin Stabilization
Plasmid-Based Generation of Induced Neural Stem Cells from Adult Human Fibroblasts
The Molecular Basis for Species-specific Activation of Human TRPA1 Protein by Protons Involves Poorly Conserved Residues within Transmembrane Domains 5 and 6
Therapeutic Potential of Mesenchymal Stromal Cells and MSC Conditioned Medium in Amyotrophic Lateral Sclerosis (ALS) - In Vitro Evidence from Primary Motor Neuron Cultures, NSC-34 Cells, Astrocytes and Microglia