Area of research
Genetics · Pathology and Forensic Medicine
Research interest
Research interests include Genetic factors in colorectal cancer, BRCA gene mutations in cancer, Glioma Diagnosis and Treatment, and Cancer Genomics and Diagnostics.
Patterns of hypermutation shape tumorigenesis and immunotherapy response in mismatch-repair-deficient glioma
Clinical and biological landscape of constitutional mismatch-repair deficiency syndrome: an International Replication Repair Deficiency Consortium cohort study
Combined Immunotherapy Improves Outcome for Replication-Repair-Deficient (RRD) High-Grade Glioma Failing Anti–PD-1 Monotherapy: A Report from the International RRD Consortium
Genomic predictors of response to PD-1 inhibition in children with germline DNA replication repair deficiency
Colorectal cancer incidences in Lynch syndrome: a comparison of results from the prospective lynch syndrome database and the international mismatch repair consortium
Diagnostic criteria for constitutional mismatch repair deficiency (CMMRD): recommendations from the international consensus working group
Variation in the risk of colorectal cancer in families with Lynch syndrome: a retrospective cohort study
Survival Benefit for Individuals With Constitutional Mismatch Repair Deficiency Undergoing Surveillance
DNA Polymerase and Mismatch Repair Exert Distinct Microsatellite Instability Signatures in Normal and Malignant Human Cells
Cancers from Novel <i>Pole</i> -Mutant Mouse Models Provide Insights into Polymerase-Mediated Hypermutagenesis and Immune Checkpoint Blockade
Comprehensive Analysis of Hypermutation in Human Cancer
PMS2 monoallelic mutation carriers: the known unknown
Patients with Lynch Syndrome Mismatch Repair Gene Mutations Are at Higher Risk for Not Only Upper Tract Urothelial Cancer but Also Bladder Cancer