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Manfred Gessler

University of Würzburg · DE
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Area of research
Molecular Biology · Pulmonary and Respiratory Medicine
Research interest
Research interests include Renal and related cancers, Renal cell carcinoma treatment, Developmental Biology and Gene Regulation, and Congenital heart defects research.
h-index
66
citations
18,306
works
286
NIH funding
primary concept
email

Recent publications

Distinct pathways for genetic and epigenetic predisposition in familial and bilateral Wilms tumor
Genome Medicine 2025cited by 12position: lastdoi
Advancing sarcoma diagnostics with expanded DNA methylation-based classification
medRxiv 2025cited by 3position: middledoi
Genomic characterization of DICER1-associated neoplasms uncovers molecular classes
Nature Communications 2023cited by 45position: middledoi
Hallmark discoveries in the biology of Wilms tumour
Nature Reviews Urology 2023cited by 25position: middledoi
The genomic landscape of pediatric renal cell carcinomas
iScience 2022cited by 8position: middledoi
Sarcoma classification by DNA methylation profiling
Nature Communications 2021cited by 536position: middledoi
Characteristics and outcome of pediatric renal cell carcinoma patients registered in the International Society of Pediatric Oncology (<scp>SIOP</scp>) 93‐01, 2001 and <scp>UK‐IMPORT</scp> database: A report of the <scp>SIOP‐Renal</scp> Tumor Study Group
International Journal of Cancer 2021cited by 42position: middledoi
Fifty years of clinical and research studies for childhood renal tumors within the International Society of Pediatric Oncology (SIOP)
Annals of Oncology 2021cited by 27position: middledoi
Identification and Analyses of Extra-Cranial and Cranial Rhabdoid Tumor Molecular Subgroups Reveal Tumors with Cytotoxic T Cell Infiltration
Cell Reports 2019cited by 118position: middledoi
The landscape of genomic alterations across childhood cancers
Nature 2018cited by 1,589position: middledoi
Primary intracranial spindle cell sarcoma with rhabdomyosarcoma-like features share a highly distinct methylation profile and DICER1 mutations
Acta Neuropathologica 2018cited by 139position: middledoi
Array-based DNA-methylation profiling in sarcomas with small blue round cell histology provides valuable diagnostic information
Modern Pathology 2018cited by 108position: middledoi
Recurrent intragenic rearrangements of EGFR and BRAF in soft tissue tumors of infants
Nature Communications 2018cited by 108position: middledoi
Author Correction: The landscape of genomic alterations across childhood cancers
Nature 2018cited by 28position: middledoi
REGGAE: a novel approach for the identification of key transcriptional regulators
Bioinformatics 2018cited by 9position: middledoi
Rationale for the treatment of Wilms tumour in the UMBRELLA SIOP–RTSG 2016 protocol
Nature Reviews Urology 2017cited by 374position: middledoi
Gene expression profiles of brain endothelial cells during embryonic development at bulk and single-cell levels
Science Signaling 2017cited by 139position: lastdoi
The transcriptional repressor Hes1 attenuates inflammation by regulating transcription elongation
Nature Immunology 2016cited by 90position: middledoi
Mutations in the SIX1/2 Pathway and the DROSHA/DGCR8 miRNA Microprocessor Complex Underlie High-Risk Blastemal Type Wilms Tumors
Cancer Cell 2015cited by 306position: lastdoi
Multiple mechanisms of MYCN dysregulation in Wilms tumour
Oncotarget 2015cited by 105position: middledoi
Abstract A1-59: Multiple mechanisms of MYCN dysregulation in Wilms tumor
Cancer Research 2015cited by 1position: middledoi
Abstract A1-67: Prognostic significance of copy number aberrations in Wilms tumor
Cancer Research 2015cited by 0position: middledoi
Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death
Nature Genetics 2013cited by 545position: middledoi
COUP-TFII orchestrates venous and lymphatic endothelial identity by homo- or hetero-dimerisation with PROX1
Journal of Cell Science 2013cited by 80position: middledoi
Characterization of the chromosomal translocation t(10;17)(q22;p13) in clear cell sarcoma of kidney
The Journal of Pathology 2012cited by 140position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Norbert Graf · Saarland University8 papers (2012–2022)Harm van Tinteren · Metastatic Breast Cancer Network5 papers (2015–2021)Kathy Pritchard‐Jones · Great Ormond Street Hospital5 papers (2015–2021)Jenny Wegert · University of Würzburg5 papers (2015–2022)Marry M. van den Heuvel‐Eibrink · Nationwide Children's Hospital4 papers (2015–2021)Gordan Vujanić · University Hospital Heidelberg4 papers (2015–2017)Ivo Leuschner · University of Lübeck3 papers (2012–2017)David Gisselsson · Lund University3 papers (2015–2015)Tasnim Chagtai · University Hospital Heidelberg3 papers (2015–2015)Christophe Bergeron · Université Claude Bernard Lyon 13 papers (2015–2021)Marcel Kool · European Bioinformatics Institute3 papers (2015–2015)Christian Rübe · Saarland University2 papers (2017–2021)David Jones · Mayo Clinic in Florida2 papers (2022–2023)Sergey Popov · University Hospital Heidelberg2 papers (2015–2015)Richard D. Williams · Clinical Trials New Zealand2 papers (2015–2015) · 2 papers (2015–2015)Filippo Spreafico · University of Padua2 papers (2017–2021)John Apps · Medical College of Wisconsin2 papers (2015–2015)Maureen J. O’Sullivan · Trinity College Dublin2 papers (2012–2015)Jan Godziński · Medical University of Silesia2 papers (2017–2021)
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