Area of research
Pulmonary and Respiratory Medicine · Molecular Biology
Research interest
Research focused on Cancer research and Pancreatic cancer, with related work in CRISPR, Anterior cingulate cortex, Enhancer. Notable publications include 'Post-mortem molecular profiling of three psychiatric disorders', 'Occupancy maps of 208 chromatin-associated proteins in one human cell type', and 'RNA sequencing of pancreatic adenocarcinoma tumors yields novel expression patterns associated with long‐term survival and reveals a role for ANGPTL4'.
Blood-based tumor mutational burden impacts clinical outcomes of immune checkpoint inhibitor treated breast and prostate cancers
Long-read genome sequencing for the molecular diagnosis of neurodevelopmental disorders
Pooled CRISPR screening in pancreatic cancer cells implicates co-repressor complexes as a cause of multiple drug resistance via regulation of epithelial-to-mesenchymal transition
Occupancy maps of 208 chromatin-associated proteins in one human cell type
CRISPR/Cas9-targeted removal of unwanted sequences from small-RNA sequencing libraries
Population‐Specific Patterns of Epigenetic Defects in the B Cell Lineage in Patients With Systemic Lupus Erythematosus
De novo mutations in the GTP/GDP-binding region of RALA, a RAS-like small GTPase, cause intellectual disability and developmental delay
Discovery and Validation of Circulating Biomarkers of Colorectal Adenoma by High-Depth Small RNA Sequencing
Post-mortem molecular profiling of three psychiatric disorders
RNA sequencing-based cell proliferation analysis across 19 cancers identifies a subset of proliferation-informative cancers with a common survival signature
aRNApipe: a balanced, efficient and distributed pipeline for processing RNA-seq data in high-performance computing environments
RNA sequencing of pancreatic adenocarcinoma tumors yields novel expression patterns associated with long‐term survival and reveals a role for<i>ANGPTL4</i>
Genomic regulation of invasion by STAT3 in triple negative breast cancer
Distinct gene regulatory programs define the inhibitory effects of liver X receptors and PPARG on cancer cell proliferation
Differential stress induced c-Fos expression and identification of region-specific miRNA-mRNA networks in the dorsal raphe and amygdala of high-responder/low-responder rats
Identification and function of enhancers in the human genome
Kinase Gene Expression Profiling of Metastatic Clear Cell Renal Cell Carcinoma Tissue Identifies Potential New Therapeutic Targets