Area of research
Cell Biology · Molecular Biology
Research interest
Research focused on Cell biology and Effector, with related work in Infrared, MAPK/ERK pathway, Enteropathogenic Escherichia coli. Notable publications include 'Live imaging of GLUT2 glucose-dependent trafficking and its inhibition in polarized epithelial cysts', 'Mitochondrial Targeting of the Enteropathogenic Escherichia coli Map Triggers Calcium Mobilization, ADAM10-MAP Kinase Signaling, and Host Cell Apoptosis', and 'Retraction of enteropathogenic E. coli type IV pili promotes efficient host cell colonization, effector translocation and tight junction disruption'.
EspH utilizes phosphoinositide and Rab binding domains to interact with plasma membrane infection sites and Rab GTPases*
Mitogen-Activated Protein Kinases (MAPKs) and Enteric Bacterial Pathogens: A Complex Interplay
Enteropathogenic <i>E. coli</i> infection co-elicits lysosomal exocytosis and lytic host cell death
Topology and function of translocated EspZ
EspH interacts with the host active Bcr related (ABR) protein to suppress RhoGTPases
Type <scp>III</scp> secreted effectors that target mitochondria
Mitochondrial Targeting of the Enteropathogenic Escherichia coli Map Triggers Calcium Mobilization, ADAM10-MAP Kinase Signaling, and Host Cell Apoptosis
Enteropathogenic Escherichia coli remodels host endosomes to promote endocytic turnover and breakdown of surface polarity
EspH Suppresses Erk by Spatial Segregation from CD81 Tetraspanin Microdomains
Live imaging of GLUT2 glucose-dependent trafficking and its inhibition in polarized epithelial cysts
Real-Time Sensing of Enteropathogenic E. coli-Induced Effects on Epithelial Host Cell Height, Cell-Substrate Interactions, and Endocytic Processes by Infrared Surface Plasmon Spectroscopy
Retraction of enteropathogenic E. coli type IV pili promotes efficient host cell colonization, effector translocation and tight junction disruption
Quantitative surface plasmon spectroscopy: Determination of the infrared optical constants of living cells
Real-Time Sensing of Cell Morphology by Infrared Waveguide Spectroscopy
Infrared surface plasmon spectroscopy and biosensing