Area of research
Genetics · Cancer Research
Research interest
Research interests include Glioma Diagnosis and Treatment, Cancer, Hypoxia, and Metabolism, ATP Synthase and ATPases Research, and Epigenetics and DNA Methylation.
Advancing sarcoma diagnostics with expanded DNA methylation-based classification
Papillary tumor of the pineal region: analysis of DNA methylation profiles and clinical outcomes in 76 cases
Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways
Clinical, genomic, and epigenomic analyses of H3K27M-mutant diffuse midline glioma long-term survivors reveal a distinct group of tumors with MAPK pathway alterations
Common molecular features of H3K27M DMGs and PFA ependymomas map to hindbrain developmental pathways
High-grade glioma with pleomorphic and pseudopapillary features (HPAP): a proposed type of circumscribed glioma in adults harboring frequent TP53 mutations and recurrent monosomy 13
Expanded analysis of high-grade astrocytoma with piloid features identifies an epigenetically and clinically distinct subtype associated with neurofibromatosis type 1
Multiplatform molecular analyses refine classification of gliomas arising in patients with neurofibromatosis type 1
Molecular and clinicopathologic characteristics of gliomas with EP300::BCOR fusions
Recurrent ACVR1 mutations in posterior fossa ependymoma
Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas
Epigenetically defined therapeutic targeting in H3.3G34R/V high-grade gliomas
Purine metabolism regulates DNA repair and therapy resistance in glioblastoma
Integrated Metabolic and Epigenomic Reprograming by H3K27M Mutations in Diffuse Intrinsic Pontine Gliomas
Tremelimumab in combination with ablation in patients with advanced hepatocellular carcinoma