Area of research
Immunology · Cell Biology
Research interest
Research focused on Endosome and Retromer, with related work in Cell biology, GSK-3, Cancer. Notable publications include 'Regulation of WASH-Dependent Actin Polymerization and Protein Trafficking by Ubiquitination', 'CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL', and 'Retromer Binding to FAM21 and the WASH Complex Is Perturbed by the Parkinson Disease-Linked VPS35(D620N) Mutation'.
Germline mutations in a G protein identify signaling cross-talk in T cells
The hepatic WASH complex is required for efficient plasma LDL and HDL cholesterol clearance
<i>Trans</i>-endocytosis elicited by nectins transfers cytoplasmic cargo, including infectious material, between cells
NK cell defects in X-linked pigmentary reticulate disorder
Molecular Pathways: Revisiting Glycogen Synthase Kinase-3β as a Target for the Treatment of Cancer
Macrogenomic engineering via modulation of the scaling of chromatin packing density
CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL
Structural and mechanistic insights into regulation of the retromer coat by TBC1d5
GSK-3 inhibition overcomes chemoresistance in human breast cancer
GSK-3β Governs Inflammation-Induced NFATc2 Signaling Hubs to Promote Pancreatic Cancer Progression
NFATc1 Links EGFR Signaling to Induction of Sox9 Transcription and Acinar–Ductal Transdifferentiation in the Pancreas
HkRP3 Is a Microtubule-Binding Protein Regulating Lytic Granule Clustering and NK Cell Killing
Identification of HDAC6‐Selective Inhibitors of Low Cancer Cell Cytotoxicity
Retromer Binding to FAM21 and the WASH Complex Is Perturbed by the Parkinson Disease-Linked VPS35(D620N) Mutation
Retromer Binding to FAM21 and the WASH Complex Is Perturbed by the Parkinson Disease-Linked VPS35(D620N) Mutation
Regulation of WASH-Dependent Actin Polymerization and Protein Trafficking by Ubiquitination
Epigenetic Regulation of Autophagy by the Methyltransferase G9a
Inhibition of GSK-3 Induces Differentiation and Impaired Glucose Metabolism in Renal Cancer
Multiple repeat elements within the FAM21 tail link the WASH actin regulatory complex to the retromer