Area of research
Neurology · Physiology
Research interest
Research interests include Parkinson's Disease Mechanisms and Treatments, Lysosomal Storage Disorders Research, Cellular transport and secretion, and Neurological disorders and treatments.
CLN7/MFSD8 may be an important factor for SARS-CoV-2 cell entry
Patient-Customized Oligonucleotide Therapy for a Rare Genetic Disease
Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson’s disease
Dopamine induces soluble α-synuclein oligomers and nigrostriatal degeneration
α-Synuclein–induced lysosomal dysfunction occurs through disruptions in protein trafficking in human midbrain synucleinopathy models
Activation of -Glucocerebrosidase Reduces Pathological -Synuclein and Restores Lysosomal Function in Parkinson's Patient Midbrain Neurons
Parkin and PINK1 Patient iPSC-Derived Midbrain Dopamine Neurons Exhibit Mitochondrial Dysfunction and α-Synuclein Accumulation
The Glycolytic Enzyme, GPI, Is a Functionally Conserved Modifier of Dopaminergic Neurodegeneration in Parkinson’s Models
Identification and Rescue of α-Synuclein Toxicity in Parkinson Patient–Derived Neurons
Pharmacological Rescue of Mitochondrial Deficits in iPSC-Derived Neural Cells from Patients with Familial Parkinson’s Disease
Sirt1 Mediates Neuroprotection from Mutant Huntingtin by Activation of TORC1 and CREB Transcriptional Pathway
Deficiency of ATP13A2 Leads to Lysosomal Dysfunction, α-Synuclein Accumulation, and Neurotoxicity
<i>Glucocerebrosidase</i> mutations in a <scp>S</scp>erbian <scp>P</scp>arkinson's disease population