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James J. Lah

Emory Healthcare · US
Area of research
Physiology · Psychiatry and Mental health
Research interest
Research interests include Alzheimer's disease research and treatments, Dementia and Cognitive Impairment Research, Functional Brain Connectivity Studies, and Neuroinflammation and Neurodegeneration Mechanisms.
h-index
100
citations
40,701
works
516
NIH funding
primary concept
Medicine
email

Recent publications

The relationship of soluble tau species with Alzheimer's disease amyloid plaque removal and tau pathology
Alzheimer s & Dementia 2025cited by 3position: middledoi
Proteomic analysis of Alzheimer’s disease cerebrospinal fluid reveals alterations associated with <i>APOE</i> ε4 and atomoxetine treatment
Science Translational Medicine 2024cited by 48position: middledoi
Proteomic changes in the human cerebrovasculature in Alzheimer's disease and related tauopathies linked to peripheral biomarkers in plasma and cerebrospinal fluid
Alzheimer s & Dementia 2024cited by 37position: middledoi
Differential DNA methylation in the brain as potential mediator of the association between traffic‐related PM<sub>2.5</sub> and neuropathology markers of Alzheimer's disease
Alzheimer s & Dementia 2024cited by 28position: middledoi
Association between Fine Particulate Matter Exposure and Cerebrospinal Fluid Biomarkers of Alzheimer’s Disease among a Cognitively Healthy Population-Based Cohort
Environmental Health Perspectives 2024cited by 25position: middledoi
Bridging the gap: Multi‐omics profiling of brain tissue in Alzheimer's disease and older controls in multi‐ethnic populations
Alzheimer s & Dementia 2024cited by 24position: middledoi
Heparin-enriched plasma proteome is significantly altered in Alzheimer’s disease
Molecular Neurodegeneration 2024cited by 20position: middledoi
Network proteomics of the Lewy body dementia brain reveals presynaptic signatures distinct from Alzheimer’s disease
Molecular Neurodegeneration 2024cited by 17position: middledoi
Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer’s disease
Nature Medicine 2023cited by 168position: middledoi
Quantitative Mass Spectrometry Analysis of Cerebrospinal Fluid Protein Biomarkers in Alzheimer’s Disease
Scientific Data 2023cited by 71position: middledoi
Quantitative proteomics of cerebrospinal fluid from African Americans and Caucasians reveals shared and divergent changes in Alzheimer’s disease
Molecular Neurodegeneration 2023cited by 71position: middledoi
A protein panel in cerebrospinal fluid for diagnostic and predictive assessment of Alzheimer’s disease
Science Translational Medicine 2023cited by 68position: middledoi
Unbiased classification of the elderly human brain proteome resolves distinct clinical and pathophysiological subtypes of cognitive impairment
Neurobiology of Disease 2023cited by 48position: middledoi
Relationships of Cognitive Measures with Cerebrospinal Fluid but Not Imaging Biomarkers of Alzheimer Disease Vary between Black and White Individuals
Annals of Neurology 2023cited by 18position: middledoi
Large-scale deep multi-layer analysis of Alzheimer’s disease brain reveals strong proteomic disease-related changes not observed at the RNA level
Nature Neuroscience 2022cited by 598position: middledoi
Multi-platform proteomic analysis of Alzheimer’s disease cerebrospinal fluid and plasma reveals network biomarkers associated with proteostasis and the matrisome
Alzheimer s Research & Therapy 2022cited by 187position: middledoi
CSF proteome profiling across the Alzheimer’s disease spectrum reflects the multifactorial nature of the disease and identifies specific biomarker panels
Nature Aging 2022cited by 98position: middledoi
Automated analysis of facial emotions in subjects with cognitive impairment
PLoS ONE 2022cited by 54position: middledoi
The complex relationship of air pollution and neighborhood socioeconomic status and their association with cognitive decline
Environment International 2022cited by 39position: middledoi
Neighborhood characteristics as confounders and effect modifiers for the association between air pollution exposure and subjective cognitive functioning
Environmental Research 2022cited by 28position: middledoi
Brain microRNAs are associated with variation in cognitive trajectory in advanced age
Translational Psychiatry 2022cited by 26position: middledoi
Alzheimer's disease genetic burden is associated with mid‐life depression among persons with normal cognition
Alzheimer s & Dementia 2022cited by 15position: middledoi
Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer’s disease pathogenesis
Nature Genetics 2021cited by 395position: middledoi
A trial of gantenerumab or solanezumab in dominantly inherited Alzheimer’s disease
Nature Medicine 2021cited by 362position: middledoi
Brain proteome-wide association study implicates novel proteins in depression pathogenesis
Nature Neuroscience 2021cited by 172position: middledoi
A feasibility trial of gamma sensory flicker for patients with prodromal Alzheimer's disease
Alzheimer s & Dementia Translational Research & Clinical Interventions 2021cited by 126position: middledoi
Extracellular signal‐regulated kinase regulates microglial immune responses in Alzheimer’s disease
Journal of Neuroscience Research 2021cited by 112position: middledoi
A phase II study repurposing atomoxetine for neuroprotection in mild cognitive impairment
Brain 2021cited by 94position: middledoi
Genetic Evidence Supporting a Causal Role of Depression in Alzheimer’s Disease
Biological Psychiatry 2021cited by 65position: middledoi
Atlas of RNA editing events affecting protein expression in aged and Alzheimer’s disease human brain tissue
Nature Communications 2021cited by 60position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Allan I. Levey · Emory Healthcare76 papers (2012–2024)Nicholas T. Seyfried · Emory Healthcare54 papers (2012–2024)Eric B. Dammer · Emory University50 papers (2012–2024)Duc M. Duong · Emory University48 papers (2012–2024)Marla Gearing · Emory Healthcare24 papers (2012–2024)Thomas S. Wingo · Institute for Neurodegenerative Disorders20 papers (2015–2024)Erik C. B. Johnson · Emory University15 papers (2018–2024)Aliza P. Wingo · VA Northern California Health Care System14 papers (2019–2024)Chadwick M. Hales · Emory University12 papers (2013–2021)Lingyan Ping · Emory University12 papers (2018–2024)Madhav Thambisetty · National Institute on Aging10 papers (2013–2020)Juan C. Troncoso · Johns Hopkins Hospital9 papers (2013–2020)Luming Yin · Emory and Henry College9 papers (2016–2024)Ekaterina S. Gerasimov · University of California, Davis8 papers (2020–2024)Philip L. De Jager · Mayo Clinic in Florida8 papers (2019–2023)Srikant Rangaraju · Yale University7 papers (2017–2024)Jonathan D. Glass · Emory University7 papers (2012–2020)Lenora Higginbotham · Emory University6 papers (2012–2024)Nicholas T. Seyfried · Emory University5 papers (2013–2024)Rafi U. Haque · Emory University5 papers (2020–2023)