Area of research
Pediatrics, Perinatology and Child Health · Obstetrics and Gynecology
Research interest
Research interests include Birth, Development, and Health, Gestational Diabetes Research and Management, Epigenetics and DNA Methylation, and Pregnancy and preeclampsia studies.
Childhood gut microbiome is linked to internalizing symptoms at school age via the functional connectome
Short-term diet intervention comprising of olive oil, vitamin D, and omega-3 fatty acids alters the small non-coding RNA (sncRNA) landscape of human sperm
Trigonelline is an NAD+ precursor that improves muscle function during ageing and is reduced in human sarcopenia
The Singapore National Precision Medicine Strategy
Multigenerational adversity impacts on human gut microbiome composition and socioemotional functioning in early childhood
Plasma lipidomic profiling reveals metabolic adaptations to pregnancy and signatures of cardiometabolic risk: a preconception and longitudinal cohort study
A five-safes approach to a secure and scalable genomics data repository
Analysis of clinically relevant variants from ancestrally diverse Asian genomes
Maternal Glycemic Dysregulation During Pregnancy and Neonatal Blood DNA Methylation: Meta-analyses of Epigenome-Wide Association Studies
Variability in newborn telomere length is explained by inheritance and intrauterine environment
Population-based plasma lipidomics reveals developmental changes in metabolism and signatures of obesity risk: a mother-offspring cohort study
Independent phenotypic plasticity axes define distinct obesity sub-types
Machine Learning–Derived Prenatal Predictive Risk Model to Guide Intervention and Prevent the Progression of Gestational Diabetes Mellitus to Type 2 Diabetes: Prediction Model Development Study
Maternal Prenatal Anxiety and the Fetal Origins of Epigenetic Aging
<i>Myo</i>-Inositol, Probiotics, and Micronutrient Supplementation From Preconception for Glycemia in Pregnancy: NiPPeR International Multicenter Double-Blind Randomized Controlled Trial
A compromised developmental trajectory of the infant gut microbiome and metabolome in atopic eczema
Cohort profile: Singapore Preconception Study of Long-Term Maternal and Child Outcomes (S-PRESTO)
Ethnic diversity in infant gut microbiota is apparent before the introduction of complementary diets
COVID-19 endocrinopathy with hindsight from SARS
Implication of gut microbiota in the association between infant antibiotic exposure and childhood obesity and adiposity accumulation
Mismatch between poor fetal growth and rapid postnatal weight gain in the first 2 years of life is associated with higher blood pressure and insulin resistance without increased adiposity in childhood: the GUSTO cohort study
Mitochondrial oxidative capacity and NAD+ biosynthesis are reduced in human sarcopenia across ethnicities
The PedBE clock accurately estimates DNA methylation age in pediatric buccal cells
Large-Scale Whole-Genome Sequencing of Three Diverse Asian Populations in Singapore
Metabolism of 13C-Labeled Fatty Acids in Term Human Placental Explants by Liquid Chromatography–Mass Spectrometry
circASXL1-1 regulates BAP1 deubiquitinase activity in leukemia
Myo-inositol alters 13C-labeled fatty acid metabolism in human placental explants
Optimizing drug combinations against multiple myeloma using a quadratic phenotypic optimization platform (QPOP)
The early care environment and DNA methylome variation in childhood
Effects of Antenatal Maternal Depressive Symptoms and Socio-Economic Status on Neonatal Brain Development are Modulated by Genetic Risk