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Nicolai J. Birkbak

Aarhus University · DK
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Area of research
Cancer Research · Molecular Biology
Research interest
Research interests include Cancer Genomics and Diagnostics, DNA Repair Mechanisms, Cancer Immunotherapy and Biomarkers, and Gene expression and cancer classification.
h-index
69
citations
32,076
works
312
NIH funding
primary concept
Medicine
email

Recent publications

Ultrasensitive ctDNA detection for preoperative disease stratification in early-stage lung adenocarcinoma
Nature Medicine 2025cited by 75position: middledoi
The evolution of lung cancer and impact of subclonal selection in TRACERx
Nature 2023cited by 300position: middledoi
RETRACTED ARTICLE: Antibodies against endogenous retroviruses promote lung cancer immunotherapy
Nature 2023cited by 247position: middledoi
The evolution of non-small cell lung cancer metastases in TRACERx
Nature 2023cited by 230position: middledoi
Body composition and lung cancer-associated cachexia in TRACERx
Nature Medicine 2023cited by 123position: middledoi
A local human Vδ1 T cell population is associated with survival in nonsmall-cell lung cancer
Nature Cancer 2022cited by 111position: middledoi
Pervasive chromosomal instability and karyotype order in tumour evolution
Nature 2020cited by 401position: middledoi
Interplay between whole-genome doubling and the accumulation of deleterious alterations in cancer evolution
Nature Genetics 2020cited by 275position: middledoi
The T cell differentiation landscape is shaped by tumour mutations in lung cancer
Nature Cancer 2020cited by 102position: middledoi
Representative Sequencing: Unbiased Sampling of Solid Tumor Tissue
Cell Reports 2020cited by 75position: middledoi
Publisher Correction: Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse
Nature Medicine 2020cited by 3position: middledoi
Publisher Correction: Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer
Nature Medicine 2020cited by 1position: middledoi
Artificial intelligence in cancer imaging: Clinical challenges and applications
CA A Cancer Journal for Clinicians 2019cited by 1,806position: middledoi
Neoantigen-directed immune escape in lung cancer evolution
Nature 2019cited by 968position: middledoi
Predicting response to cancer immunotherapy using noninvasive radiomic biomarkers
Annals of Oncology 2019cited by 552position: middledoi
A clonal expression biomarker associates with lung cancer mortality
Nature Medicine 2019cited by 135position: middledoi
Chromosomal instability drives metastasis through a cytosolic DNA response
Nature 2018cited by 1,531position: middledoi
Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal
Cell 2018cited by 664position: middledoi
Migrating the SNP array-based homologous recombination deficiency measures to next generation sequencing data of breast cancer
npj Breast Cancer 2018cited by 315position: middledoi
Overexpression of BLM promotes DNA damage and increased sensitivity to platinum salts in triple-negative breast and serous ovarian cancers
Annals of Oncology 2018cited by 60position: firstdoi
Tracking the Evolution of Non–Small-Cell Lung Cancer
New England Journal of Medicine 2017cited by 2,410position: middledoi
Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution
Nature 2017cited by 1,872position: middledoi
Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution
Cell 2017cited by 1,311position: middledoi
Evolution and clinical impact of co-occurring genetic alterations in advanced-stage EGFR-mutant lung cancers
Nature Genetics 2017cited by 577position: middledoi
Revisiting inconsistency in large pharmacogenomic studies
F1000Research 2017cited by 76position: middledoi
Intratumoural evolutionary landscape of high-risk prostate cancer: the PROGENY study of genomic and immune parameters
Annals of Oncology 2017cited by 62position: middledoi
Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade
Science 2016cited by 3,084position: middledoi
Revisiting inconsistency in large pharmacogenomic studies
F1000Research 2016cited by 101position: middledoi
Assessment of pharmacogenomic agreement
F1000Research 2016cited by 35position: middledoi
Clonal status of actionable driver events and the timing of mutational processes in cancer evolution
Science Translational Medicine 2015cited by 709position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Hugo J.W.L. Aerts · Harvard University7 papers (2013–2019)John Quackenbush · Brigham and Women's Hospital6 papers (2012–2017)Zoltán Szállási · Semmelweis University6 papers (2014–2018) · 5 papers (2014–2018)Benjamin Haibe‐Kains · Structural Genomics Consortium5 papers (2013–2017)Charles Swanton · Cancer Evolution and Genome Instability Laboratory5 papers (2015–2020)Nehmé El-Hachem · McGill University Health Centre4 papers (2013–2017)Andrew H. Beck · Marietta College4 papers (2013–2017) · 4 papers (2014–2018) · 4 papers (2014–2018)Christos Hatzis · University of Crete4 papers (2014–2017)Anna Goldenberg · Allen Institute for Artificial Intelligence3 papers (2016–2017)Zhaleh Safikhani · Roswell Park Comprehensive Cancer Center3 papers (2016–2017)Leming Shi · Fudan University3 papers (2016–2017)Nicholas McGranahan · London Cancer3 papers (2015–2020)Petr Smirnov · European Molecular Biology Organization3 papers (2016–2017)J. Dirk Iglehart · Brigham and Women's Hospital2 papers (2012–2018)Zhigang C. Wang · Dezhou University2 papers (2012–2015) · 2 papers (2016–2017) · 2 papers (2014–2015)
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