Area of research
Cardiology and Cardiovascular Medicine · Radiology, Nuclear Medicine and Imaging
Research interest
Research interests include Cardiovascular Function and Risk Factors, Cardiac Imaging and Diagnostics, Nitric Oxide and Endothelin Effects, and Cardiac Ischemia and Reperfusion.
Impairment of local metabolic coronary control involves perfusion-contraction matching not supply-demand imbalance.
Colchicine Alleviates Non-Atherosclerotic Vascular Aging by Targeting Endothelial Dysfunction and Inflammatory Status.
Sex and gender differences in coronary pathophysiology and ischaemic heart disease.
Vascular (dys)function in the failing heart
Vascular (dys)function in the failing heart.
FoxO1-zDHHC4-CD36 S-Acylation Axis Drives Metabolic Dysfunction in Diabetes
FoxO1-zDHHC4-CD36 S-Acylation Axis Drives Metabolic Dysfunction in Diabetes.
Microvascular Occlusion and Postrecanalization Hyperperfusion in a Swine Model of Acute Ischemic Stroke.
Potassium as an electro-metabolic signal for local coronary vasodilation.
Induction of cardiac fibulin-4 protects against pressure overload-induced cardiac hypertrophy and heart failure.
Atherosclerosis on a Chip: A 3-Dimensional Microfluidic Model of Early Arterial Events in Human Plaques
Atherosclerosis on a Chip: A 3-Dimensional Microfluidic Model of Early Arterial Events in Human Plaques.
Spatial lipidomics of coronary atherosclerotic plaque development in a familial hypercholesterolemia swine model
Vasodilator reactive oxygen species ameliorate perturbed myocardial oxygen delivery in exercising swine with multiple comorbidities.
Perivascular adipose tissue as a source of therapeutic targets and clinical biomarkers
DNA repair in cardiomyocytes is critical for maintaining cardiac function in mice.
Higher Order Singular Value Decomposition Filter for Contrast Echocardiography
A complex three-dimensional microfluidic model that mimics the early stage events in the human atherosclerotic artery
Preclinicaltrials.eu: prospective registration of animal studies.
Comparison of Large Animal Models for Acute Ischemic Stroke: Which Model to Use?
Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC Working Group on Myocardial Function and the ESC Working Group on Cellular Biology of the Heart
Utrecht University Repository (Utrecht University) 2022cited by 66position: middle
Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC Working Group on Myocardial Function and the ESC Working Group on Cellular Biology of the Heart.
Mechanisms, therapeutic implications, and methodological challenges of gut microbiota and cardiovascular diseases: a position paper by the ESC Working Group on Coronary Pathophysiology and Microcirculation.
Prevalence of microvascular angina among patients with stable symptoms in the absence of obstructive coronary artery disease: a systematic review.
Functional and structural adaptations of the coronary macro- and microvasculature to regular aerobic exercise by activation of physiological, cellular, and molecular mechanisms: ESC Working Group on Coronary Pathophysiology and Microcirculation position paper.
Preregistration of animal research protocols: development and 3-year overview of preclinicaltrials.eu
Integrated control of coronary blood flow in exercising swine by adenosine, nitric oxide, and K<sub>ATP</sub> channels.
Exercise and hypoxia unmask pulmonary vascular disease and right ventricular dysfunction in a 10- to 12-week-old swine model of neonatal oxidative injury.
Endothelial function in cardiovascular medicine: a consensus paper of the European Society of Cardiology Working Groups on Atherosclerosis and Vascular Biology, Aorta and Peripheral Vascular Diseases, Coronary Pathophysiology and Microcirculation, and Thrombosis.
Towards standardization of echocardiography for the evaluation of left ventricular function in adult rodents: a position paper of the ESC Working Group on Myocardial Function.