Area of research
Genetics · Molecular Biology
Research interest
Research focused on RANKL and Immune system, with related work in Immunotherapy, Mesenchymal stem cell, Cancer stem cell. Notable publications include 'Reshaping the systemic tumor immune environment (STIE) and tumor immune microenvironment (TIME) to enhance immunotherapy efficacy in solid tumors', 'Mesenchymal Stem Cells and Cancer: Clinical Challenges and Opportunities', and 'Lgr5 in cancer biology: functional identification of Lgr5 in cancer progression and potential opportunities for novel therapy'.
Tauroursodeoxycholic acid regulates macrophage/monocyte distribution and improves spinal microenvironment to promote nerve regeneration through inhibiting NF-κB signaling pathway in spinal cord injury
Atractylenolide I Attenuates Glucocorticoid-Induced Osteoporosis via Inhibiting NF-κB Signaling Pathway
Histone demethylase KDM5C is critical for cartilage development and protects against osteoarthritis by increasing HIF-1α to maintain mitochondrial function
Qi-Gui-Jian-Gu Decoction Accelerates Osteogenesis and Fracture Healing by Activating the Wnt/β-Catenin Signaling Pathway
The relationship between mindful self-care and maternal-fetal attachment in pregnant women: the parallel mediating effects of positive and negative affect
Huo Xue Tong Luo capsule epigenetically activates β-catenin, promotes Prx1-lineage cells proliferation and endochondral bone formation during fracture healing
DBDPE inhibits myogenic differentiation of C2C12 cells through inhibiting mitochondrial function and PI3K/AKT/mTOR signaling pathway
Corylifol A suppresses osteoclastogenesis and alleviates ovariectomy-induced bone loss via attenuating ROS production and impairing mitochondrial function
Stigmasterol mitigates estrogen-deficiency-induced osteoporosis through inhibition of phosphorylated p65 and MAPK signaling pathways
Salvianolic Acid B Accelerates Osteoporotic Fracture Healing <i>via</i> LncRNA-MALAT1/miR-155-5p/HIF1A Axis
Shen Gu An Capsule Inhibition of Postmenopausal Osteoporosis in Ovariectomized Mice Using Network Pharmacology-Based Mechanism Prediction and Pharmacological Validation
Advances in immunology and immunotherapy for mesenchymal gastrointestinal cancers
Isoimperatorin attenuates bone loss by inhibiting the binding of RANKL to RANK
Ginsenoside compound-K attenuates OVX-induced osteoporosis via the suppression of RANKL-induced osteoclastogenesis and oxidative stress
Syringic acid promotes cartilage extracellular matrix generation and attenuates osteoarthritic cartilage degradation by activating <scp>TGF</scp>‐β/Smad and inhibiting <scp>NF‐κB</scp> signaling pathway
Isoliensinine suppresses bone loss by targeted inhibition of RANKL-RANK binding
Histone demethylase Kdm5c regulates osteogenesis and bone formation via PI3K/Akt/HIF1α and Wnt/β-catenin signaling pathways
Retraction Note: Polydatin improves osteogenic differentiation of human bone mesenchymal stem cells by stimulating TAZ expression via BMP2-Wnt/β-catenin signaling pathway
Reshaping the systemic tumor immune environment (STIE) and tumor immune microenvironment (TIME) to enhance immunotherapy efficacy in solid tumors
Osteoimmunology: The correlation between osteoclasts and the Th17/Treg balance in osteoporosis
Copper regulation of immune response and potential implications for treating orthopedic disorders
Dehydromiltirone inhibits osteoclast differentiation in RAW264.7 and bone marrow macrophages by modulating MAPK and NF-κB activity
Nonwoven-based gelatin/polycaprolactone membrane loaded with ERK inhibitor U0126 for treatment of tendon defects
A Novel RANKL‐Targeted Furoquinoline Alkaloid Ameliorates Bone Loss in Ovariectomized Osteoporosis through Inhibiting the NF‐<i>κ</i>B Signal Pathway and Reducing Reactive Oxygen Species
Bu Shen Huo Xue decoction promotes functional recovery in spinal cord injury mice by improving the microenvironment to promote axonal regeneration
Bushen huoxue decoction inhibits RANKL-stimulated osteoclastogenesis and glucocorticoid-induced bone loss by modulating the NF-κB, ERK, and JNK signaling pathways
Tauroursodeoxycholic acid alleviates secondary injury in spinal cord injury mice by reducing oxidative stress, apoptosis, and inflammatory response
Cyasterone accelerates fracture healing by promoting MSCs migration and osteogenesis
MicroRNA-21: An Emerging Player in Bone Diseases
Hydroxysafflor yellow A promotes osteogenesis and bone development via epigenetically regulating β-catenin and prevents ovariectomy-induced bone loss