Area of research
Molecular Biology · Ophthalmology
Research interest
Research focused on Mitochondrial DNA and Optic neuropathy, with related work in Retinal degeneration, Neurodegeneration, CHOP. Notable publications include 'Gene delivery to mitochondria by targeting modified adenoassociated virus suppresses Leber’s hereditary optic neuropathy in a mouse model', 'Glucose Regulated Protein 78 Diminishes α-Synuclein Neurotoxicity in a Rat Model of Parkinson Disease', and 'Drug and Gene Delivery to the Back of the Eye: From Bench to Bedside'.
R9-SOCS1-KIR Peptide Abrogates Lipopolysaccharide Mediated Inflammation: Implications for the Treatment of Endotoxin Induced Uveitis
Investigative Ophthalmology & Visual Science 2021cited by 0position: last
Longterm Reversal of Severe Visual Loss by Mitochondrial Gene Transfer in a Mouse Model of Leber Hereditary Optic Neuropathy
Consequences of zygote injection and germline transfer of mutant human mitochondrial DNA in mice
Ablation of Chop Transiently Enhances Photoreceptor Survival but Does Not Prevent Retinal Degeneration in Transgenic Mice Expressing Human P23H Rhodopsin
Drug and Gene Delivery to the Back of the Eye: From Bench to Bedside
Safety and Effects of the Vector for the Leber Hereditary Optic Neuropathy Gene Therapy Clinical Trial
LHON Gene Therapy Vector Prevents Visual Loss and Optic Neuropathy Induced by G11778A Mutant Mitochondrial DNA: Biodistribution and Toxicology Profile
Ablation of C/EBP Homologous Protein Does Not Protect T17M RHO Mice from Retinal Degeneration
NADH-dehydrogenase Type-2 Suppresses Irreversible Visual Loss and Neurodegeneration in the EAE Animal Model of MS
Gene delivery to mitochondria by targeting modified adenoassociated virus suppresses Leber’s hereditary optic neuropathy in a mouse model
Glucose Regulated Protein 78 Diminishes α-Synuclein Neurotoxicity in a Rat Model of Parkinson Disease
Mutant NADH dehydrogenase subunit 4 gene delivery to mitochondria by targeting sequence-modified adeno-associated virus induces visual loss and optic atrophy in mice.
PubMed 2012cited by 44position: middle