Area of research
Cardiology and Cardiovascular Medicine · Molecular Biology
Research interest
Research interests include Cardiac electrophysiology and arrhythmias, Ion channel regulation and function, Cardiac Ischemia and Reperfusion, and Nitric Oxide and Endothelin Effects.
Piezo1 channel activation stimulates ATP production through enhancing mitochondrial respiration and glycolysis in vascular endothelial cells
Anthelmintic nitazoxanide protects against experimental pulmonary fibrosis
Repurposing nitazoxanide as a novel anti‐atherosclerotic drug based on mitochondrial uncoupling mechanisms
Anthelmintic niclosamide attenuates pressure-overload induced heart failure in mice
Chemical mitochondrial uncouplers share common inhibitory effect on NLRP3 inflammasome activation through inhibiting NFκB nuclear translocation
The different response of cardiomyocytes and cardiac fibroblasts to mitochondria inhibition and the underlying role of STAT3
Injectable pegylated niclosamide (polyethylene glycol‐modified niclosamide) for cancer therapy
Niclosamide ethanolamine induces trachea relaxation and inhibits proliferation and migration of trachea smooth muscle cells
Characterizations of mitochondrial uncoupling induced by chemical mitochondrial uncouplers in cardiomyocytes
Niclosamide inhibits vascular smooth muscle cell proliferation and migration and attenuates neointimal hyperplasia in injured rat carotid arteries
Mitochondrial Fission Inhibitors Suppress Endothelin-1-Induced Artery Constriction
Design, synthesis and characterization of poly (methacrylic acid-niclosamide) and its effect on arterial function
Azo polymeric micelles designed for colon-targeted dimethyl fumarate delivery for colon cancer therapy
GDF11/BMP11 activates both smad1/5/8 and smad2/3 signals but shows no significant effect on proliferation and migration of human umbilical vein endothelial cells
Mitochondrial uncoupler carbonyl cyanide m‐chlorophenylhydrazone induces vasorelaxation without involving K<sub>ATP</sub>channel activation in smooth muscle cells of arteries
Mitochondrial Fission of Smooth Muscle Cells Is Involved in Artery Constriction
Niclosamide ethanolamine inhibits artery constriction
Taurochenodeoxycholate relaxes rat mesenteric arteries through activating eNOS: Comparing with glycochenodeoxycholate and tauroursodeoxycholate
Dimethyl fumarate induces necroptosis in colon cancer cells through <scp>GSH</scp> depletion/<scp>ROS</scp> increase/<scp>MAPKs</scp> activation pathway
Calcium-Activated Potassium Channels
Bone morphogenetic protein-4: a novel therapeutic target for pathological cardiac hypertrophy/heart failure
The potential role of Kv4.3 K <sup>+</sup> channel in heart hypertrophy
Bone Morphogenetic Protein‐2 Antagonizes Bone Morphogenetic Protein‐4 Induced Cardiomyocyte Hypertrophy and Apoptosis
Oestrogen inhibits <scp>BMP</scp>4‐induced <scp>BMP</scp>4 expression in cardiomyocytes: a potential mechanism of oestrogen‐mediated protection against cardiac hypertrophy
(4‐[6‐(4‐isopropoxyphenyl)pyrazolo [1,5‐a]pyrimidin‐3‐yl] quinoline) is a novel inhibitor of autophagy
DMH1 Increases Glucose Metabolism through Activating Akt in L6 Rat Skeletal Muscle Cells
Bone morphogenetic protein-4 induces upregulation of Cav3.1 Ca2+ channels in HL-1 atrial myocytes
Insulin prevents bone morphogenetic protein-4 induced cardiomyocyte apoptosis through activating Akt
From Nitric Oxide to Hyperbaric Oxygen
3-Methyladenine induces cell death and its interaction with chemotherapeutic drugs is independent of autophagy