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James Chavez

California Institute for Regenerative Medicine ·
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Area of research
Hematology · Immunology
Research interest
Research focused on Haematopoiesis and Cell biology, with related work in Olaparib, Cancer research, Transformation (genetics). Notable publications include 'PU.1 enforces quiescence and limits hematopoietic stem cell expansion during inflammatory stress', 'Inhibition of DOCK1 prevents the clonal expansion of high-risk TP53-mutant clonal hematopoiesis induced by genotoxic stressors', and '3053 – ENGINEERING SEQUENTIAL MUTATIONS INTO HUMAN HSPCS YIELDS AN AGGRESSIVE MYELOID MALIGNANCY ALLOWING FOR INTERROGATION OF PRELEUKEMIC TRANSFORMATION'.
h-index
citations
95
works
3
NIH funding
primary concept
email

Recent publications

Inhibition of DOCK1 prevents the clonal expansion of high-risk TP53-mutant clonal hematopoiesis induced by genotoxic stressors.
Blood 2025cited by 1position: middledoi
3053 – ENGINEERING SEQUENTIAL MUTATIONS INTO HUMAN HSPCS YIELDS AN AGGRESSIVE MYELOID MALIGNANCY ALLOWING FOR INTERROGATION OF PRELEUKEMIC TRANSFORMATION
Experimental Hematology 2024cited by 0position: middledoi
PU.1 enforces quiescence and limits hematopoietic stem cell expansion during inflammatory stress
The Journal of Experimental Medicine 2021cited by 94position: firstdoi

Grants

No grants ingested yet.

Frequent collaborators

Cailin Collins · Palo Alto University2 papers (2024–2025)Ravindra Majeti · Stanford University2 papers (2024–2025) · 1 papers (2021–2021)Timm Schroeder · ETH Zurich1 papers (2021–2021)Yusuke Nakauchi · California Institute for Regenerative Medicine1 papers (2024–2024)Rajiv Sharma · Northwell Health1 papers (2024–2024)Hyunmin Kim · University of Colorado Denver1 papers (2021–2021)Feifei Zhao · Hebei Medical University1 papers (2024–2024)Suyoun Choi · California Institute for Regenerative Medicine1 papers (2024–2024)Thomas Koehnke · California Institute for Regenerative Medicine1 papers (2024–2024)Brown Patrick · California Institute for Regenerative Medicine1 papers (2025–2025)Emma Heaton · California Institute for Regenerative Medicine1 papers (2025–2025) · 1 papers (2021–2021)Taylor Mills · University of Colorado Denver1 papers (2021–2021) · 1 papers (2021–2021) · 1 papers (2021–2021)Andrew J. Gentles · Stanford University1 papers (2025–2025)Pavel Davizon‐Castillo · University of Washington1 papers (2021–2021)Kensuke Kayamori · Palo Alto University1 papers (2025–2025)Dirk Loeffler · University of Tennessee at Knoxville1 papers (2021–2021)
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