Area of research
Pulmonary and Respiratory Medicine · Cancer Research
Research interest
Research interests include Prostate Cancer Treatment and Research, Cancer, Lipids, and Metabolism, Estrogen and related hormone effects, and Heat shock proteins research.
Circular RMST cooperates with lineage-driving transcription factors to govern neuroendocrine transdifferentiation
UCHL1 is a potential molecular indicator and therapeutic target for neuroendocrine carcinomas
Abstract 6574: UCHL1 is a molecular indicator and a therapeutic target for neuroendocrine carcinomas
MYC is a regulator of androgen receptor inhibition-induced metabolic requirements in prostate cancer
Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase
Drug-Induced Epigenomic Plasticity Reprograms Circadian Rhythm Regulation to Drive Prostate Cancer toward Androgen Independence
The 5-Hydroxymethylcytosine Landscape of Prostate Cancer
Reprogramming of the FOXA1 cistrome in treatment-emergent neuroendocrine prostate cancer
An androgen receptor switch underlies lineage infidelity in treatment-resistant prostate cancer
The long noncoding RNA H19 regulates tumor plasticity in neuroendocrine prostate cancer
CRISPRi screens reveal a DNA methylation-mediated 3D genome dependent causal mechanism in prostate cancer
Opposing transcriptional programs of KLF5 and AR emerge during therapy for advanced prostate cancer
The DNA methylation landscape of advanced prostate cancer
Trop2 is a driver of metastatic prostate cancer with neuroendocrine phenotype via PARP1
Androgen deprivation upregulates SPINK1 expression and potentiates cellular plasticity in prostate cancer
The Role of Lineage Plasticity in Prostate Cancer Therapy Resistance
ONECUT2 is a driver of neuroendocrine prostate cancer
Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer
Cellular plasticity and the neuroendocrine phenotype in prostate cancer
Risk SNP-Mediated Promoter-Enhancer Switching Drives Prostate Cancer through lncRNA PCAT19
The long noncoding RNA landscape of neuroendocrine prostate cancer and its clinical implications
Role of Androgen Receptor Variants in Prostate Cancer: Report from the 2017 Mission Androgen Receptor Variants Meeting
LSD1-Mediated Epigenetic Reprogramming Drives CENPE Expression and Prostate Cancer Progression
The Master Neural Transcription Factor BRN2 Is an Androgen Receptor–Suppressed Driver of Neuroendocrine Differentiation in Prostate Cancer
Clusterin as a therapeutic target
The Placental Gene PEG10 Promotes Progression of Neuroendocrine Prostate Cancer
From sequence to molecular pathology, and a mechanism driving the neuroendocrine phenotype in prostate cancer