Area of research
Hematology · Molecular Biology
Research interest
Research interests include Acute Myeloid Leukemia Research, Retinoids in leukemia and cellular processes, Cancer Genomics and Diagnostics, and CAR-T cell therapy research.
EVEREST-2: Initial data of the logic-gated Tmod chimeric antigen receptor T-cell (CAR T) therapy A2B694 for patients with solid tumors associated with mesothelin (MSLN) expression and with human leukocyte antigen (HLA) loss of heterozygosity (LOH).
535 EVEREST-2: a phase 1/2 study of A2B694, a logic-gated Tmod CAR T therapy to treat solid tumors expressing mesothelin (MSLN) with HLA-A*02 loss of heterozygosity: initial safety and efficacy results
Detecting HLA loss of heterozygosity within a standard diagnostic sequencing workflow for prognostic and therapeutic opportunities
EVEREST-2: A seamless phase 1/2 study of A2B694, a mesothelin (MSLN) logic-gated Tmod CAR T-cell therapy, in patients with solid tumors that show MSLN expression and human leukocyte antigen (HLA)-A*02 loss of heterozygosity (LOH).
A global study for acute myeloid leukemia with <i>RARG</i> rearrangement
639 BASECAMP-1: Leveraging HLA loss of heterozygosity in solid tumors by NGS to identify patients with relapsed solid tumors for future CEA and MSLN logic-gated Tmod™ CAR T-cell therapy
<i>TP53</i> and Decitabine in Acute Myeloid Leukemia and Myelodysplastic Syndromes
Genomic analysis of germ line and somatic variants in familial myelodysplasia/acute myeloid leukemia
Age-related mutations associated with clonal hematopoietic expansion and malignancies
Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia
Mutational landscape and significance across 12 major cancer types
Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing
The Origin and Evolution of Mutations in Acute Myeloid Leukemia
Tetrafluoro(trifluoromethyl)sulfanes Chemical Reactivity and Polar Hyrdophobicity
I-Corps: Novel Monomers and Chemistries for Photopolymerization of Coatings and Adhesives
Control of Conformation and Reactivity in Pentafluorosulfanyl and Tetrafluorosulfanyl Substituted Aliphatic Compounds
The Preparation and Utility of Pentafluorosulfanyl Substituted Aliphatic Compounds
Purchase of 400 MHz NMR Spectrometer
Acquisition of CCD-Based X-Ray Diffractometer
New Strategies for the Enantioselective Synthesis of Fluorinated Molecules
Stereo- and Enantioselective Synthesis with Fluorinated Reagents
Enantioselective Reactions of Fluorinated Reagents (Chemistry)
Fy 81 Science Faculty Professional Development Program