Pedro Saavedra

Area of research

Molecular Biology · Immunology

Research interest

Research focused on Inflammasome and Efferocytosis, with related work in Phagocytosis, Cell biology, Cachexia. Notable publications include 'IL1β Promotes Immune Suppression in the Tumor Microenvironment Independent of the Inflammasome and Gasdermin D', 'Metabolic adaptation supports enhanced macrophage efferocytosis in limited-oxygen environments', and 'Escherichia coli Rho GTPase-activating toxin CNF1 mediates NLRP3 inflammasome activation via p21-activated kinases-1/2 during bacteraemia in mice'.

h-index

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citations

334

works

NIH funding

—

primary concept

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Recent publications

Early life high fructose impairs microglial phagocytosis and neurodevelopment

Nature 2025cited by 18position: middledoi

Broad-spectrum antibiotics disrupt homeostatic efferocytosis

Nature Metabolism 2024cited by 14position: firstdoi

Metabolic adaptation supports enhanced macrophage efferocytosis in limited-oxygen environments

Cell Metabolism 2022cited by 85position: middledoi

Cancer cachexia: lessons from <i>Drosophila</i>

Disease Models & Mechanisms 2022cited by 48position: middledoi

Escherichia coli Rho GTPase-activating toxin CNF1 mediates NLRP3 inflammasome activation via p21-activated kinases-1/2 during bacteraemia in mice

Nature Microbiology 2021cited by 74position: middledoi

IL1β Promotes Immune Suppression in the Tumor Microenvironment Independent of the Inflammasome and Gasdermin D

Cancer Immunology Research 2020cited by 95position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Justin S. A. Perry · University of California, Riverside3 papers (2022–2025)— · 3 papers (2022–2025)Christopher D. Lucas · University of Edinburgh3 papers (2022–2025)Alissa Trzeciak · New York University3 papers (2022–2025)Jon Iker Etchegaray · Gladstone Institutes2 papers (2022–2025)Allie Lipshutz · Weill Cornell Medicine2 papers (2024–2025)Kayvan R. Keshari · Memorial Sloan Kettering Cancer Center2 papers (2022–2025)Zhaoquan Wang · Memorial Sloan Kettering Cancer Center2 papers (2024–2025)— · 2 papers (2024–2025)— · 1 papers (2024–2024)Frédéric Geissmann · Memorial Sloan Kettering Cancer Center1 papers (2025–2025)— · 1 papers (2024–2024)Ying Liu · Hebei Medical University1 papers (2022–2022)Yating Wang · Wuhan University1 papers (2022–2022)Yanting Chen · Hainan Eye Hospital1 papers (2022–2022)Ann K Baako · Memorial Sloan Kettering Cancer Center1 papers (2025–2025)— · 1 papers (2025–2025)— · 1 papers (2021–2021)Raymond Ruimy · Université Claude Bernard Lyon 11 papers (2021–2021)Els Verhoeyen · Université Claude Bernard Lyon 11 papers (2021–2021)