Area of research
Molecular Biology · Materials Chemistry
Research interest
Research interests include DNA Repair Mechanisms, DNA and Nucleic Acid Chemistry, Mitochondrial Function and Pathology, and Enzyme Structure and Function.
Mitochondrial Transcription: A click-chemistry derived detection methodology forgoing the use of radiation in in vitro analyses
Fidelity of Ribonucleotide Incorporation by the SARS-CoV-2 Replication Complex.
A minimal motif for sequence recognition by mitochondrial transcription factor A (TFAM).
Characterization of Aurintricarboxylic Acid (ATA) Interactions with Plasma Transporter Protein and SARS-CoV-2 Viral Targets: Correlation of Functional Activity and Binding Energetics.
Checkpoint-mediated DNA polymerase ε exonuclease activity curbing counteracts resection-driven fork collapse.
Enzymatic β-Oxidation of the Cholesterol Side Chain in <i>Mycobacterium tuberculosis</i> Bifurcates Stereospecifically at Hydration of 3-Oxo-cholest-4,22-dien-24-oyl-CoA.
A549 cells contain enlarged mitochondria with independently functional clustered mtDNA nucleoids.
Enzymatic β-Oxidation of the Cholesterol Side Chain in Mycobacterium Tuberculosis Bifurcates Stereospecifically at Hydration of 3-Oxo-Cholest-4,22- Dien-24-Oyl-CoA
Mitochondrial genetic variation is enriched in G-quadruplex regions that stall DNA synthesis in vitro.
Post-translational Succinylation of <i>Mycobacterium tuberculosis</i> Enoyl-CoA Hydratase EchA19 Slows Catalytic Hydration of Cholesterol Catabolite 3-Oxo-chol-4,22-diene-24-oyl-CoA.
Mechanisms of mammalian mitochondrial transcription.
The juxtamembrane linker in neutral sphingomyelinase-2 functions as an intramolecular allosteric switch that activates the enzyme.
Correction to: HnRNPA2 is a novel histone acetyltransferase that mediates mitochondrial stress-induced nuclear gene expression.
Structural and Biochemical Basis for Intracellular Kinase Inhibition by Src-specific Peptidic Macrocycles
Organization of the human mitochondrial transcription initiation complex