Area of research
Physiology · Spectroscopy
Research interest
Research focused on Mass spectrometry imaging and Isoelectric point, with related work in CD36, Mass spectrometry, Krabbe disease. Notable publications include 'Isoelectric Point Separations of Peptides and Proteins', 'CD36 maintains lipid homeostasis via selective uptake of monounsaturated fatty acids during matrix detachment and tumor progression', and 'Activated Mesenchymal Stem Cells Induce Recovery Following Stroke Via Regulation of Inflammation and Oligodendrogenesis'.
Cholesterol-targeting Wnt–β-catenin signaling inhibitors for colorectal cancer
The ocular surface tear film as a biomarker for systemic health
Cerebellar lipid dysregulation in SCA3: A comparative study in patients and mice
Neutrophils exposed to a cholesterol metabolite secrete extracellular vesicles that promote epithelial-mesenchymal transition and stemness in breast cancer cells
mTOR inhibition reprograms cellular lipid homeostasis by inducing alternative lipid uptake and promoting cholesterol transport
Gel-assisted mass spectrometry imaging enables sub-micrometer spatial lipidomics
Accumulation of alkyl-lysophosphatidylcholines in Niemann-Pick disease type C1
Proteomics insights into fragile X syndrome: Unraveling molecular mechanisms and therapeutic avenues
Identifying the crucial binding domain of histatin-1 to recombinant TMEM97 in activating chemotactic migration in human corneal epithelial cells
Follicular fluid aids cell adhesion, spreading in an age independent manner and shows an age-dependent effect on DNA damage in fallopian tube epithelial cells
CD36 maintains lipid homeostasis via selective uptake of monounsaturated fatty acids during matrix detachment and tumor progression
SMART: A data reporting standard for mass spectrometry imaging
Identification of cerebral spinal fluid protein biomarkers in Niemann-Pick disease, type C1
An Integrated Approach to Protein Discovery and Detection From Complex Biofluids
Discovery of a Small-Molecule Modulator of the Autophagy-Lysosome Pathway That Targets Lamin A/C and LAMP1, Induces Autophagic Flux, and Affects Lysosome Positioning in Neurons
Elevated cerebrospinal fluid ubiquitin C-terminal hydrolase-L1 levels correlate with phenotypic severity and therapeutic response in Niemann-Pick disease, type C1
α-Synuclein-dependent increases in PIP5K1γ drive inositol signaling to promote neurotoxicity
3D Quantification of Elemental Gradients within Heterostructured Particles of Battery Cathodes
Reduced endothelial caveolin-1 underlies deficits in brain insulin signalling in type 2 diabetes
A differential proteomics study of cerebrospinal fluid from individuals with Niemann‐Pick disease, Type C1
PHY34 inhibits autophagy through V-ATPase V0A2 subunit inhibition and CAS/CSE1L nuclear cargo trafficking in high grade serous ovarian cancer
Targeting lipid–protein interaction to treat Syk-mediated acute myeloid leukemia
Steroid hormones of the octopus self-destruct system
Lipidomic analysis identifies age-disease-related changes and potential new biomarkers in brain-derived extracellular vesicles from metachromatic leukodystrophy mice
Species-specific differences in NPC1 protein trafficking govern therapeutic response in Niemann-Pick type C disease
The Pathogenic Sphingolipid Psychosine is Secreted in Extracellular Vesicles in the Brain of a Mouse Model of Krabbe Disease
PAX8 modulates the tumor microenvironment of high grade serous ovarian cancer through changes in the secretome
Mass spectrometry-based proteomics in neurodegenerative lysosomal storage disorders
Visualizing Cholesterol in the Brain by On-Tissue Derivatization and Quantitative Mass Spectrometry Imaging
Waning efficacy in a long-term AAV-mediated gene therapy study in the murine model of Krabbe disease