Area of research
Spectroscopy · Molecular Biology
Research interest
Research interests include Protein Structure and Dynamics, Advanced NMR Techniques and Applications, NMR spectroscopy and applications, and Molecular spectroscopy and chirality.
Two-conformer equilibrium of maltose-binding protein in the absence of ligand from residual dipolar coupling analysis.
Solution Domain Dynamics of Monomeric SARS-CoV‑2 Main Protease Revealed by Optimized NMR Residual Dipolar Coupling Measurements.
Structure of a transient protein-folding intermediate by pressure-jump NMR spectroscopy.
Chemical Analysis of Deep-Lung Fluid Derived from Exhaled Breath Particles.
3D-printed microcell for protein NMR at high ionic strengths and small sample volumes
3D-printed microcell for protein NMR at high ionic strengths and small sample volumes.
Proline Peptide Bond Isomerization in Ubiquitin Under Folding and Denaturing Conditions by Pressure-Jump NMR.
Targeting the Main Protease (M<sup>pro</sup>, nsp5) by Growth of Fragment Scaffolds Exploiting Structure-Based Methodologies.
Snoring-generated fluid droplets as a potential mechanistic link between sleep-disordered breathing and pneumonia.
In Memoriam: Professor Vladimír Sklenář (April 16, 1951 – April 13, 2024)
From Milliseconds to Minutes: Melittin Self-Assembly from Concerted Non-Equilibrium Pressure-Jump and Equilibrium Relaxation Nuclear Magnetic Resonance.
Resolving the Loss of Intermediate-Size Speech Aerosols in Funnel-Guided Particle Counting Measurement.
SARS-CoV-2 omicron variants harbor spike protein mutations responsible for their attenuated fusogenic phenotype.
Validation of X-ray Crystal Structure Ensemble Representations of SARS-CoV-2 Main Protease by Solution NMR Residual Dipolar Couplings.
Experimental NOE, Chemical Shift, and Proline Isomerization Data Provide Detailed Insights into Amelotin Oligomerization.
Recombinant Expression and Chemical Amidation of Isotopically Labeled Native Melittin.
Synergism between x-ray crystallography and NMR residual dipolar couplings in characterizing protein dynamics.
Advances in NMR Spectroscopy of Weakly Aligned Biomolecular Systems.
Comprehensive Fragment Screening of the SARS‐CoV‐2 Proteome Explores Novel Chemical Space for Drug Development
Quantitative detection of hydrogen peroxide in rain, air, exhaled breath, and biological fluids by NMR spectroscopy.
Comprehensive Fragment Screening of the SARS-CoV-2 Proteome Explores Novel Chemical Space for Drug Development.
Hybrid measurement of respiratory aerosol reveals a dominant coarse fraction resulting from speech that remains airborne for minutes.
NMR Observation of Sulfhydryl Signals in SARS-CoV-2 Main Protease Aids Structural Studies.
Comprehensive Fragment Screening of the SARS‐CoV‐2 Proteome Explores Novel Chemical Space for Drug Development
Simultaneous Quantification of H<sub>2</sub>O<sub>2</sub> and Organic Hydroperoxides by <sup>1</sup>H NMR Spectroscopy.
Snoring may transmit infectious aerosols from the upper to the lower respiratory tract.
Real-time Exchange of the Lipid-bound Intermediate and Post-fusion States of the HIV-1 gp41 Ectodomain.