Area of research
Molecular Biology · Physiology
Research interest
Research interests include Telomeres, Telomerase, and Senescence, Extracellular vesicles in disease, Ubiquitin and proteasome pathways, and RNA modifications and cancer.
Extrachromosomal DNA–Driven Oncogene Dosage Heterogeneity Promotes Rapid Adaptation to Therapy in <i>MYCN</i> -Amplified Cancers
USP10 drives cancer stemness and enables super-competitor signalling in colorectal cancer
USP28 controls SREBP2 and the mevalonate pathway to drive tumour growth in squamous cancer
Stabilisation of β-Catenin-WNT signalling by USP10 in APC- <i>truncated</i> colorectal cancer drives cancer stemness and enables super-competitor signalling
The glucose transporter GLUT3 controls T helper 17 cell responses through glycolytic-epigenetic reprogramming
Diabetes Mellitus Is a Possible Risk Factor for Nodo-paranodopathy With Antiparanodal Autoantibodies
Acute systemic knockdown of <i>Atg7</i> is lethal and causes pancreatic destruction in shRNA transgenic mice
MiR-205-driven downregulation of cholesterol biosynthesis through SQLE-inhibition identifies therapeutic vulnerability in aggressive prostate cancer
LXRα activation and Raf inhibition trigger lethal lipotoxicity in liver cancer
Cutaneous epithelioid haemangiomas show somatic mutations in the mitogen‐activated protein kinase pathway
LUBAC determines chemotherapy resistance in squamous cell lung cancer
Senescence Sensitivity of Breast Cancer Cells Is Defined by Positive Feedback Loop between CIP2A and E2F1