Area of research
Cancer Research · Epidemiology
Research interest
Research focused on Cancer research and G protein-coupled bile acid receptor, with related work in Bile acid, Farnesoid X receptor, Autophagy. Notable publications include 'Hyocholic acid species improve glucose homeostasis through a distinct TGR5 and FXR signaling mechanism', 'HIF-1α-induced expression of m6A reader YTHDF1 drives hypoxia-induced autophagy and malignancy of hepatocellular carcinoma by promoting ATG2A and ATG14 translation', and 'IL-6 promotes PD-L1 expression in monocytes and macrophages by decreasing protein tyrosine phosphatase receptor type O expression in human hepatocellular carcinoma'.
Conjugated Lithocholic Acid Activates Hepatic TGR5 to Promote Lipotoxicity and MASLD‐MASH Transition by Disrupting Carnitine Biosynthesis
HIF-1α-induced expression of m6A reader YTHDF1 drives hypoxia-induced autophagy and malignancy of hepatocellular carcinoma by promoting ATG2A and ATG14 translation
Conjugated secondary 12α-hydroxylated bile acids promote liver fibrogenesis
Hyocholic acid species improve glucose homeostasis through a distinct TGR5 and FXR signaling mechanism
IL-6 promotes PD-L1 expression in monocytes and macrophages by decreasing protein tyrosine phosphatase receptor type O expression in human hepatocellular carcinoma
RP11-323N12.5 promotes the malignancy and immunosuppression of human gastric cancer by increasing YAP1 transcription
Dysregulated bile acid signaling contributes to the neurological impairment in murine models of acute and chronic liver failure