Area of research
Surgery · Transplantation
Research interest
Research focused on Xenotransplantation and Transplantation, with related work in Immunology, Allotransplantation, Immune system. Notable publications include 'Justification of specific genetic modifications in pigs for clinical organ xenotransplantation', 'Xenotransplantation—the current status and prospects', and 'Life-supporting Kidney Xenotransplantation From Genetically Engineered Pigs in Baboons: A Comparison of Two Immunosuppressive Regimens'.
What Therapeutic Regimen Will Be Optimal for Initial Clinical Trials of Pig Organ Transplantation?
The Genetically Engineered Heart as a Bridge to Allotransplantation in Infants Just Around the Corner?
Evidence suggesting that deletion of expression of N‐glycolylneuraminic acid (Neu5Gc) in the organ‐source pig is associated with increased antibody‐mediated rejection of kidney transplants in baboons
Initial experimental experience of triple‐knockout pig red blood cells as potential sources for transfusion in alloimmunized patients with sickle cell disease
Histopathology of pig kidney grafts with/without expression of the carbohydrate Neu5Gc in immunosuppressed baboons
Evidence that sensitization to triple‐knockout pig cells will not be detrimental to subsequent allotransplantation
The Role of Interleukin-6 (IL-6) in the Systemic Inflammatory Response in Xenograft Recipients and in Pig Kidney Xenograft Failure
Old World Monkeys are less than ideal transplantation models for testing pig organs lacking three carbohydrate antigens (Triple-Knockout)
Pig kidney xenotransplantation: Progress toward clinical trials
The final obstacle to successful pre‐clinical xenotransplantation?
Evidence for GTKO/β4GalNT2KO Pigs as the Preferred Organ-source for Old World Nonhuman Primates as a Preclinical Model of Xenotransplantation
Effect of intravenous immunoglobulin (IVIg) on primate complement-dependent cytotoxicity of genetically engineered pig cells: relevance to clinical xenotransplantation
The problem of the “4th xenoantigen” after pig organ transplantation in non‐human primates may be overcome by expression of human “protective” proteins
Justification of specific genetic modifications in pigs for clinical organ xenotransplantation
Life-supporting Kidney Xenotransplantation From Genetically Engineered Pigs in Baboons: A Comparison of Two Immunosuppressive Regimens
Clinical Pig Kidney Xenotransplantation: How Close Are We?
Is interleukin-6 receptor blockade (tocilizumab) beneficial or detrimental to pig-to-baboon organ xenotransplantation?
Anti-Pig Antibody in Infants: Can a Genetically Engineered Pig Heart Bridge to Allotransplantation?
Skin xenotransplantation: Historical review and clinical potential
Episodes of hypovolemia/dehydration in baboons with pig kidney transplants: A new syndrome of clinical importance?
Bringing Home The Bacon: Update on The State of Kidney Xenotransplantation
Serum amyloid a as an indicator of impending xenograft failure: Experimental studies
Xenotransplantation—the current status and prospects