Area of research
Oncology · Cancer Research
Research interest
Research interests include Colorectal Cancer Treatments and Studies, Cancer Genomics and Diagnostics, HER2/EGFR in Cancer Research, and Nuclear Structure and Function.
Defining the Antitumor Mechanism of Action of a Clinical-stage Compound as a Selective Degrader of the Nuclear Pore Complex
<i>RAS/RAF</i> Comutation and <i>ERBB2</i> Copy Number Modulates HER2 Heterogeneity and Responsiveness to HER2-directed Therapy in Colorectal Cancer
Copper induces cell death by targeting lipoylated TCA cycle proteins
RNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition
Virtual screening for small-molecule pathway regulators by image-profile matching
Discovering the anticancer potential of non-oncology drugs by systematic viability profiling
The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K
A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles
The Drug Repurposing Hub: a next-generation drug library and information resource
Abstract 1953: Accelerating prediction of pediatric and rare cancer vulnerabilities using next-generation cancer models
Systematic Functional Interrogation of Rare Cancer Variants Identifies Oncogenic Alleles