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Megan Crumbaker

Garvan Institute of Medical Research · AU
🔎 Find collaborators in Pulmonary and Respiratory Medicine · Radiology, Nuclear Medicine and Imaging →
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Area of research
Pulmonary and Respiratory Medicine · Radiology, Nuclear Medicine and Imaging
Research interest
Research interests include Prostate Cancer Treatment and Research, Radiopharmaceutical Chemistry and Applications, Prostate Cancer Diagnosis and Treatment, and Cancer, Lipids, and Metabolism.
h-index
21
citations
1,923
works
118
NIH funding
primary concept
Medicine
email

Recent publications

Overall survival and quality of life with [177Lu]Lu-PSMA-617 plus enzalutamide versus enzalutamide alone in metastatic castration-resistant prostate cancer (ENZA-p): secondary outcomes from a multicentre, open-label, randomised, phase 2 trial
The Lancet Oncology 2025cited by 50position: middledoi
Lutetium-177–PSMA-617 or cabazitaxel in metastatic prostate cancer: circulating tumor DNA analysis of the randomized phase 2 TheraP trial
Nature Medicine 2025cited by 26position: middledoi
Prognostic and predictive value of baseline PSMA-PET total tumour volume and SUVmean in metastatic castration-resistant prostate cancer in ENZA-p (ANZUP1901): a substudy from a multicentre, open-label, randomised, phase 2 trial
The Lancet Oncology 2025cited by 20position: middledoi
[177Lu]Lu-PSMA-617 plus enzalutamide in patients with metastatic castration-resistant prostate cancer (ENZA-p): an open-label, multicentre, randomised, phase 2 trial
The Lancet Oncology 2024cited by 144position: middledoi
Overall survival with [177Lu]Lu-PSMA-617 versus cabazitaxel in metastatic castration-resistant prostate cancer (TheraP): secondary outcomes of a randomised, open-label, phase 2 trial
The Lancet Oncology 2023cited by 190position: middledoi
Patient outcomes following a response biomarker-guided approach to treatment using 177Lu-PSMA-I&T in men with metastatic castrate-resistant prostate cancer (Re-SPECT)
Therapeutic Advances in Medical Oncology 2023cited by 39position: middledoi
<sup>177</sup>Lu-PSMA SPECT Quantitation at 6 Weeks (Dose 2) Predicts Short Progression-Free Survival for Patients Undergoing<sup>177</sup>Lu-PSMA-I&amp;T Therapy
Journal of Nuclear Medicine 2022cited by 68position: middledoi
Evaluation of<sup>177</sup>Lu-PSMA-617 SPECT/CT Quantitation as a Response Biomarker Within a Prospective<sup>177</sup>Lu-PSMA-617 and NOX66 Combination Trial (LuPIN)
Journal of Nuclear Medicine 2022cited by 59position: middledoi
The cell-free DNA methylome captures distinctions between localized and metastatic prostate tumors
Nature Communications 2022cited by 56position: middledoi
The Prognostic Value of Posttreatment<sup>68</sup>Ga-PSMA-11 PET/CT and<sup>18</sup>F-FDG PET/CT in Metastatic Castration-Resistant Prostate Cancer Treated with<sup>177</sup>Lu-PSMA-617 and NOX66 in a Phase I/II Trial (LuPIN)
Journal of Nuclear Medicine 2022cited by 29position: middledoi
Overcoming enzalutamide resistance in metastatic prostate cancer by targeting sphingosine kinase
EBioMedicine 2021cited by 51position: middledoi
<sup>177</sup>Lu-PSMA-617 and Idronoxil in Men with End-Stage Metastatic Castration-Resistant Prostate Cancer (LuPIN): Patient Outcomes and Predictors of Treatment Response in a Phase I/II Trial
Journal of Nuclear Medicine 2021cited by 45position: middledoi
ENZA‐p trial protocol: a randomized phase II trial using prostate‐specific membrane antigen as a therapeutic target and prognostic indicator in men with metastatic castration‐resistant prostate cancer treated with enzalutamide (ANZUP 1901)
British Journal of Urology 2021cited by 43position: middledoi
Results of a Prospective Phase 2 Pilot Trial of 177Lu–PSMA-617 Therapy for Metastatic Castration-Resistant Prostate Cancer Including Imaging Predictors of Treatment Response and Patterns of Progression
Clinical Genitourinary Cancer 2018cited by 182position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Anthony M. Joshua · Garvan Institute of Medical Research8 papers (2018–2023)Louise Emmett · Sydney Hospital7 papers (2018–2023)Andrew Nguyen · Northeastern University5 papers (2021–2023)Sarennya Pathmanandavel · UNSW Sydney5 papers (2021–2023)Martin R. Stockler · The University of Sydney5 papers (2021–2023)Peter Eu · Monash University5 papers (2018–2023) · 4 papers (2022–2023)Andrew Martin · The University of Queensland4 papers (2021–2022)Andrew O. Yam · UNSW Sydney4 papers (2021–2022)Craig Gedye · Calvary Mater Newcastle Hospital4 papers (2018–2023)Bao Ho · UNSW Sydney3 papers (2018–2022) · 3 papers (2022–2022) · 3 papers (2022–2022) · 3 papers (2022–2023) · 2 papers (2022–2023) · 2 papers (2022–2023)Shikha Sharma · University of Leicester2 papers (2022–2023)Elizabeth Hovey · Victorian Comprehensive Cancer Centre2 papers (2021–2023) · 2 papers (2022–2023)Alex Guminski · Memorial Sloan Kettering Cancer Center2 papers (2018–2023)
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