Area of research
Epidemiology · Immunology
Research interest
Research focused on Sepsis and Immunology, with related work in Septic shock, Immune system, Cytokine release syndrome. Notable publications include 'The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity', 'Current gaps in sepsis immunology: new opportunities for translational research', and 'Type I IFN immunoprofiling in COVID-19 patients'.
Monocyte HLA-DR expression in septic shock patients: insights from a 20-year real-world cohort of 1023 cases
The immunology of sepsis: translating new insights into clinical practice
Functional diversity of <i>NLRP3</i> gain-of-function mutants associated with CAPS autoinflammation
Integrated clustering of multiple immune marker trajectories reveals different immunotypes in severely injured patients
Profiling the dysregulated immune response in sepsis: overcoming challenges to achieve the goal of precision medicine
Granulocyte-macrophage colony-stimulating factor (GM-CSF) in patients presenting sepsis-induced immunosuppression: The GRID randomized controlled trial
Association of pronounced elevation of NET formation and nucleosome biomarkers with mortality in patients with septic shock
The double sides of NLRP3 inflammasome activation in sepsis
Identification of a sub-group of critically ill patients with high risk of intensive care unit-acquired infections and poor clinical course using a transcriptomic score
Vaccine breakthrough hypoxemic COVID-19 pneumonia in patients with auto-Abs neutralizing type I IFNs
T cell response against SARS-CoV-2 persists after one year in patients surviving severe COVID-19
A stratification strategy to predict secondary infection in critical illness-induced immune dysfunction: the REALIST score
Recombinant human interleukin-7 reverses T cell exhaustion ex vivo in critically ill COVID-19 patients
Class I/Class II HLA Evolutionary Divergence Ratio Is an Independent Marker Associated With Disease-Free and Overall Survival After Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia
HLA-DR expression on monocytes and outcome of anti-CD19 CAR T-cell therapy for large B-cell lymphoma
Nivolumab and interferon-γ rescue therapy to control mixed mould and bacterial superinfection after necrotizing fasciitis and septic shock
Interferon gamma as an immune modulating adjunct therapy for invasive mucormycosis after severe burn – A case report
The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity
Polyclonal expansion of TCR Vβ 21.3 <sup>+</sup> CD4 <sup>+</sup> and CD8 <sup>+</sup> T cells is a hallmark of multisystem inflammatory syndrome in children
Immune Profiling Demonstrates a Common Immune Signature of Delayed Acquired Immunodeficiency in Patients With Various Etiologies of Severe Injury*
Monocyte Trajectories Endotypes Are Associated With Worsening in Septic Patients
Longitudinal assessment of IFN-I activity and immune profile in critically ill COVID-19 patients with acute respiratory distress syndrome
Characterization of Circulating IL-10-Producing Cells in Septic Shock Patients: A Proof of Concept Study
Herpes DNAemia and TTV Viraemia in Intensive Care Unit Critically Ill Patients: A Single-Centre Prospective Longitudinal Study
Concomitant Assessment of Monocyte HLA-DR Expression and Ex Vivo TNF-α Release as Markers of Adverse Outcome after Various Injuries—Insights from the REALISM Study
Bridging animal and clinical research during SARS-CoV-2 pandemic: A new-old challenge
Monocyte <scp>CD169</scp> expression in <scp>COVID</scp>‐19 patients upon intensive care unit admission
Effects of dexamethasone on immune dysfunction and ventilator-associated pneumonia in COVID-19 acute respiratory distress syndrome: an observational study
Type I IFN immunoprofiling in COVID-19 patients
Monocytic HLA-DR expression kinetics in septic shock patients with different pathogens, sites of infection and adverse outcomes